Journal of Jilin University(Medicine Edition) ›› 2022, Vol. 48 ›› Issue (1): 33-43.doi: 10.13481/j.1671-587X.20220105
• Research in basic medicine • Previous Articles Next Articles
Chaofeng ZHOU,Shifan ZHOU,Qing TIAN,Sai WANG,Honglin LI,Chunzheng MA()
Received:
2021-05-20
Online:
2022-01-28
Published:
2022-01-17
Contact:
Chunzheng MA
E-mail:mchzh666@126.com
CLC Number:
Chaofeng ZHOU,Shifan ZHOU,Qing TIAN,Sai WANG,Honglin LI,Chunzheng MA. Effect of lncRNA-NORAD overexpression on biological behaviors of esophageal cancer Eca-109 cells and its mechanism[J].Journal of Jilin University(Medicine Edition), 2022, 48(1): 33-43.
Tab.3
Cell viabilities and number of invasion cells in various groups in up-regulated NORAD and miR-26a-5p experiment"
Group | Cell viability (η/%) | Number of invasion |
---|---|---|
PcDNA-3.1(+)+mimics NC | 45.36±5.63 | 60.82±6.72 |
PcDNA-NORAD+mimics NC | 82.48±6.58* | 120.56±7.85* |
PcDNA-3.1(+)+miR-26a-5p mimics | 23.46±6.36* | 30.58±7.83* |
PcDNA-NORAD+miR-26a-5p mimics | 60.82±6.72△ | 62.65±7.25△ |
1 | LIU H, ZHANG Q, LOU Q, et al. Differential Analysis of lncRNA, miRNA and mRNA Expression Profiles and the Prognostic Value of lncRNA in Esophageal Cancer[J]. Pathol Oncol Res, 2020,26(2): 1029-1039. |
2 | LIU T, WANG Z, ZHOU R, et al. Focally amplified lncRNA on chromosome 1 regulates apoptosis of esophageal cancer cells via DRP1 and mitochondrial dynamics[J]. IUBMB Life, 2019, 71(2): 254-260. |
3 | 牛春阳, 薛琳琳, 计红, 等. lncRNA生物学功能研究进展[J]. 中国生物制品学杂志, 2019, 32(2): 228-232. |
4 | JIAO C, SONG Z, CHEN J, et al. lncRNA-UCA1 enhances cell proliferation through functioning as a ceRNA of Sox4 in esophageal cancer[J]. Oncol Rep, 2016, 36(5): 2960-2966. |
5 | ZHENG X X, HU H B, LI S T. High expression of lncRNA PVT1 promotes invasion by inducing epithelial-to-mesenchymal transition in esophageal cancer[J]. Oncol Lett, 2016, 12(4): 2357-2362. |
6 | ZHANG J, LI X Y, HU P, et al. lncRNA NORAD contributes to colorectal cancer progression by inhibition of miR-202-5p[J]. Oncol Res, 2018, 26(9): 1411-1418. |
7 | TAO W, LI Y, ZHU M, et al. LncRNA NORAD promotes proliferation and inhibits apoptosis of gastric cancer by regulating miR-214/Akt/mTOR axis[J]. Onco Targets Ther, 2019, 12: 8841-8851. |
8 | LIANG L, ZENG J H, WANG J Y, et al. Down-regulation of miR-26a-5p in hepatocellular carcinoma: a qRT-PCR and bioinformatics study[J]. Pathol Res Pract, 2017, 213(12): 1494-1509. |
9 | GHANBARI R, REZASOLTANI S, HASHEMI J,et al.Expression analysis of previously verified fecal and plasma dow-regulated microRNAs (miR-4478,1295-3p, 142-3p and 26a-5p) in FFPE tissue samples of CRC patients[J]. Arch Iran Med, 2017, 20(2): 92-95. |
10 | FENG L L, SHEN F R, ZHOU J H, et al. Expression of the lncRNA ZFAS1 in cervical cancer and its correlation with prognosis and chemosensitivity[J]. Gene, 2019, 696: 105-112. |
11 | LIANG H, ZHANG C, GUAN H, et al. LncRNA DANCR promotes cervical cancer progression by upregulating ROCK1 via sponging miR-335-5p[J]. J Cell Physiol, 2019, 234(5): 7266-7278. |
12 | 刘远光, 刘怀海. LncRNA HULC通过miR-372/CXCR4轴来调控肝癌细胞的增殖、凋亡与上皮-间质转化[J]. 中国比较医学杂志, 2020, 30(10): 44-55. |
13 | LI Z, DING Z, RONG D, et al. Overexpression of lncRNA AFAP1-AS1 promotes cell proliferation and invasion in gastric cancer[J]. Oncol Lett, 2019, 18(3): 3211-3217. |
14 | HUANG J W, LUO X Y, LI Z H, et al. LncRNA NNT-AS1 regulates the progression of lung cancer through the NNT-AS1/miR-3666/E2F2 axis[J]. Eur Rev Med Pharmacol Sci, 2020, 24(1): 238-248. |
15 | 鲁首男, 战铁翔, 苏志雷, 等. HOXA11-AS在恶性肿瘤中的表达及作用研究[J]. 中国比较医学杂志, 2019, 29(2): 111-115. |
16 | WU X, LIM Z F, LI Z, et al. NORAD expression is associated with adverse prognosis in esophageal squamous cell carcinoma[J]. Oncol Res Treat, 2017, 40(6): 370-374. |
17 | 王思宇,王 宇.lncRNA UCA1和miRNAs在消化系统肿瘤中的作用机制研究进展[J]. 解放军医学杂志, 2021,46(12): 1232-1238. |
18 | LU Q, SHAN S, LI Y, et al. Long noncoding RNA SNHG1 promotes non-small cell lung cancer progression by up-regulating MTDH via sponging miR-145-5p[J]. Faseb J, 2018, 32(7): 3957-3967. |
19 | LUO H, XU C, LE W, et al. lncRNA CASC11 promotes cancer cell proliferation in bladder cancer through miRNA-150[J].J Cell Biochem,2019,120(8):13487-13493. |
20 | REN Y L, ZHANG W. Propofol promotes apoptosis of colorectal cancer cells via alleviating the suppression of lncRNA HOXA11-AS on miRNA let-7i[J]. Biochem Cell Biol, 2020, 98(2): 90-98. |
21 | SUN Y, ZHU Q, YANG W, et al. LncRNA H19/miR-194/PFTK1 axis modulates the cell proliferation and migration of pancreatic cancer[J]. J Cell Biochem, 2019, 120(3): 3874-3886. |
22 | 支小飞, 马利林. 肾上腺素受体调节的自噬效应在胃癌细胞增殖及抗凋亡过程中的作用及机制[J]. 临床与病理杂志, 2015(z1): 49-49. |
23 | RAJAK S, RAZA S, TEWARI A, et al. Autophagic protein ULK1 regulates FOXM1 signalling in human hepatoma cells[J]. Biochem Biophys Res Commun, 2020, 532(4): 570-575. |
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