Abstract:

Abstract:Objective To measure the area of macular foveal avascular zone(FAZ) without area vasculosa with APS-B digital fluorescein fundus angiography(FFA) and image analysis system,and provide the  normal morphological data and technique for clinical work.Methods The 49 normal eyes in 37 cases without eye diseases were detected with digital FFA. All objects of the study had clear dioptric media without retinal disease,such as  retinal hemorrhage in center of retina.The  area of  FAZ was calculated with APS-B image analysis system;the difference FAZ areas between yonger age group and older age group was compared,then  the correlationship between age and FAZ area was analyzed. Results The normal  FAZ area   was (0.32±0.09) mm2,and it was (0.23±0.07) mm2 in yonger age group,and the FAZ area in older age group was (0.26±0.11) mm2.There was no significant difference between  two groups(P＞0.05). There was no correlationship between age increasing and macular area (r=0.312,P=0.106),but there were greater differences of FAZ area between individuals.Conclusion The FAZ area obtained with APS-B digital FFA  and image analysis system   doesn’t change with age increasing.

Key words: macular;macular foveal avascular area;fluorescein fundus angiography