To reduce the frictional resistance between the barrel and the rubber seal ring of shell body during the launching process of aerodynamic extinguishing cannon, a bionic drag reduction technology of dimpled surface was applied to the rubber ring. The motion model was established for the dimpled drag reduction surface of the rubber seal ring. The effects of the characteristic diameter of bionic dimples on the rubber seal ring and the shell speed on the frictional resistance between barrel and shell body were investigated by numerical simulation. Results show that, at the same shell speed, with dimple characteristic diameter of 2 mm, the highest drag reduction effect, 17.191%, was obtained; with dimple characteristic diameter of 4 mm, the lowest drag reduction effect, 3.158, was obtained. It is revealed that the mechanism of the drag reduction is that, during moving inside the barrel, the lubricant stored in the dimples on the seal ring of shell spills over to lubricate the barrel wall and seal ring, which reduces the frictional resistance and thus increases the launching speed.