吉林大学学报(工学版) ›› 2018, Vol. 48 ›› Issue (3): 859-865.doi: 10.13229/j.cnki.jdxbgxb20170406

• Orginal Article • Previous Articles     Next Articles

Construction of disease-symptom semantic net for misdiagnosis prompt

HUANG Lan1,2, JI Lin-ying3, YAO Gang4, ZHAI Rui-feng5, BAI Tian1,2   

  1. 1.College of Computer Science and Technology,Jilin University,Changchun 130012,China;
    2.Key Laboratory of Symbol Computation and Knowledge Engineering of Ministry of Education,Jilin University,Changchun 130012,China;
    3.College of Software,Jilin University,Changchun 130012,China;
    4.Neurological Department,The Second Hospital of Jilin University,Changchun 130041,China;
    5.College of Electronical and Information Engineering,Changchun University of Science and Technology,Changchun 130022,China
  • Received:2017-04-21 Online:2018-05-20 Published:2018-05-20

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Abstract: A Disease-Symptom Semantic Net (DSSN) for misdiagnosis prompt is constructed. First, symptom words are recognized from medical corpus, and a symptom ontology based on semantic relations between symptom words is established. Then, the relations between diseases and symptoms and the misdiagnosed relations between diseases were test mined and extracted to construct DSSN. DSSN contains Disease Ontology (DO), new established symptom ontology, misdiagnosed relations between diseases and differential diagnosis knowledge. Finally, a use case in clinical diagnosis is used to illustrate that DSSN is helpful to prompt misdiagnosis in clinical assistance diagnosis system.

Key words: artificial intelligence, semantic network, text mining, misdiagnosis, ontology

CLC Number: 

  • TP182
[1] Balogh E P, Miller B T, Ball J R, et al.Improving diagnosis in healthcare[R]. Washington, DC:The National Academies Press,2015.
[2] 赵会懂. 通过误诊文献的关键词词频分析看临床误诊发生的规律[J]. 中国医学图书情报杂志,2010,19(11):73-77.
Zhao Hui-dong.Clinical misdiagnosis rules found in analysis of the frequencies of its key words appeared in misdiagnosis related papers[J]. Chinese Journal of Medical Library and Information Science,2010,19(11):73-77.
[3] Ely J W, Graber M L, Croskerry P.Checklists to reduce diagnostic errors[J]. Academic Medicine,2011,86(3):307-313.
[4] 王俊华,左万利,彭涛. 面向文本的本体学习方法[J]. 吉林大学学报:工学版,2015,45(1):237-244.
Wang Jun-hua, Zuo Wan-li, Peng Tao.Test-orinted ontology learning methods[J]. Journal of Jilin University(Engineering and Technology Edition),2015,45(1):237-244.
[5] Gene O C.The gene ontology (GO) database and informatics resource[J]. Nucleic Acids Research,2004,32(Database):D258-D261.
[6] Schriml L M, Arze C, Nadendla S, et al.Disease ontology: a backbone for disease semantic integration[J]. Nucleic Acids Research,2012,40(Database):D940-D946.
[7] Kohler S, Doelken S C, Mungall C J, et al.The human phenotype ontology project: linking molecular biology and disease through phenotype data[J]. Nucleic Acids Research,2014,42(Database):D966-D974.
[8] 刘彦斌,周春光,张重毅,等. 基于本体的语义生物信息数据库资源链接[J]. 吉林大学学报:工学版,2010,40(6):1651-1654.
Liu Yan-bin, Zhou Chun-guang,Zhang Chong-yi, et al.Resource interlinking of semantic bioinformatics database based on ontology[J]. Journal of Jilin University(Engineering and Technology Edition),2010,40(6):1651-1654.
[9] Mohammed O, Benlamri R, Fong S.Building a diseases symptoms ontology for medical diagnosis: an integrative approach[C]∥Proc of the IEEE International Conference on Future Generation Communication Technology,London,2012:104-108.
[10] Cheng L,Wang G H, Li J,et al.SIDD:a semantically integrated database towards a global view of human disease[J]. Plos One,2013,8(10):e75504.
[11] Huang Lan, Wang Ye, Wang Yan, et al.Gene-disease interaction retrieval from multiple sources: a network based method[J]. Biomed Research International,2016,2016(3):3594517.
[12] Bai Tian, Gong Lei-guang, Wang Ye, et al.A method for exploring implicit concept relatedness in biomedical knowledge network[J]. BMC Bioinformatics,2016,17(9):53-66.
[13] Jonquet C, Shah N H, Youn C H, et al.NCBO annotator: semantic annotation of biomedical data[C]∥Proc of the 8th Int Semantic Web Conf, Poster and Demonstration Session, Berlin,2009:2-3.
[14] Demner-Fushman D, Rogers W J, Aronson A R.MetaMap lite: an evaluation of a new Java implementation of MetaMap[J]. Journal of the American Medical Informatics Association,2017,24(4):841-844.
[15] Porter M F.An algorithm for suffix stripping[J]. Program Electronic Library & Information Systems,2006,14(3):130-137.
[16] Miller G A, Fellbaum C.WordNet then and now[J]. Language Resources and Evaluation,2007,41(2):209-214.
[17] Lawrence Tierney, Saint Sanjay, Whooley Mary.Current Essentials of Medicine[M].4th ed. New York:McGraw-Hill Companies,2011.
[18] Gennari J H, Musen M A, Fergerson R W, et al.The evolution of Protégé:an environment for knowledge based systems development[J]. International Journal of Human-Computer Studies,2009,58(1):89-123.
[19] 孙宝志. 临床医学导论[M].北京:高等教育出版社,2013.
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