Journal of Jilin University(Engineering and Technology Edition) ›› 2025, Vol. 55 ›› Issue (10): 3352-3360.doi: 10.13229/j.cnki.jdxbgxb.20231419

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Brain tissue segmentation method combining multi-scale and attention mechanisms

Xiu-feng ZHANG(),Yun-fei JIANG,Sheng-jin GUO,Yan-song LIU,Ling-zhuo TIAN,Shi-chen ZHANG   

  1. School of Mechanical and Electrical Engineering,Dalian Minzu University,Dalian 116600,China
  • Received:2023-12-18 Online:2025-10-01 Published:2026-02-03

Abstract:

Due to the small size and low contrast of subcortical brain structures(such as the striatum)in medical images, their segmentation is challenging, making their application in automated medical diagnosis difficult,this article proposes a medical image segmentation network based on deep learning methods to segment the three parts of the striatum, namely the globus pallidus, caudate nucleus, and putamen, in magnetic resonance imaging. The network model proposed in this article has the ability to capture global and local features and establish the correlation between global and local information, and effectively fuses deep semantic features and shallow detail features at different scales without degrading the depth, achieving accurate segmentation of the striatum. The model is validated on publicly available brain datasets and compared with other state-of-the-art methods. The model achieved dice similarity coefficient, average intersection ratio, and 95% Hausdorff distance are 94.26%, 90.94%, and 3.82 respectively, which are better than several other methods and have reached the advanced level. This shows that the model proposed in this article can improve the segmentation accuracy of the striatum and provide a basis for research on related diseases.

Key words: biomedical engineering, medical image segmentation, deep learning, multi-scale feature extraction, striatum

CLC Number: 

  • TP391.4

Fig.1

Overall structure of proposed model"

Fig.2

Dual-path feature extraction module"

Fig.3

AMFE Module structure diagram"

Table 1

DSC Comparison with advanced models"

模 型苍白球壳核尾状核平均
U-Net1291.6494.3592.5392.84
Yee等2292.2794.6293.0693.32
Ramzan等2392.7095.2192.5593.49
CAN2692.9495.5193.2093.88
TransUNet2792.6994.4093.5793.55
CoTr2891.7995.5093.5793.62
TFCNs2991.8194.6892.0792.85
EA-Net3091.0394.4593.1892.89
本文93.3295.5893.8794.26

Table 2

IoU comparison with advanced models"

模型苍白球壳核尾状核平均
U-Net1286.5289.4589.1188.36
Yee等2288.6590.3889.8389.62
Ramzan等2389.2091.1089.3589.88
CAN2689.1491.8490.0690.35
TransUNet2788.4890.2588.9789.23
CoTr2887.3391.7689.2889.46
TFCNs2987.4790.9389.5089.30
EA-Net3087.4690.6190.0489.37
本文90.2991.7990.7390.94

Table 3

95% HD comparison with advanced models"

模型苍白球壳核尾状核平均
U-Net123.664.636.454.91
Yee等223.865.045.184.69
Ramzan 等233.365.546.074.99
CAN262.984.586.234.60
TransUNet273.923.895.614.47
CoTr284.084.605.664.78
TFCNs294.475.415.695.19
EA-Net304.195.775.214.06
本文2.913.475.083.82

Table 4

Model parameters and calculation amount"

模 型参数量/M计算量/G
U-Net1225.7677.36
Yee等2231.54138.47
Ramzan等2343.71151.30
CAN2660.20178.65
TransUNet2793.19138.68
CoTr2841.92142.26
TFCNs2964.21165.45
EA-Net3051.07173.62
本文36.04117.63

Fig.4

Compare experimental visualization results"

Fig.5

DSC and IoU numerical curve"

Fig.6

95% Hausdorff distance numerical curve"

Table 5

Ablation experiment results"

模 型DiceIoUHD
Baseline92.8488.364.91
BL+DFE93.6589.304.68
BL+AMFE94.0489.694.25
本文94.2690.943.82

Fig.7

Ablation experiment visualization results"

Fig.8

3D Segmentation results"

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