[1] Perrin S. Preclinical research:Make mouse studies work[J].Nature,2014,507(7493):423-425.
[2] Shultz LD,Ishikawa F,Greiner DL.Humanized mice in translational biomedical research[J].Nat Rev Immunol,2007,7(2):118-130.
[3] McCune JM,Namikawa R,Kaneshima H,et al.The scid-hu mouse:Murine model for the analysis of human hematolymphoid differentiation and function[J].Science,1988,241:1632-1639.
[4] Mosier DE,Gulizia RJ,Baird SM,et al.Transfer of a functional human immune system to mice with severe combined immunodeficiency[J].Nature,1988,335(6187):256-259.
[5] Shultz LD,Schweitzer PA,Christianson SW,et al.Multiple defects in innate and adaptive immunologic function in nod/ltsz-scid mice[J].J Immunol,1995,154(1):180-191.
[6] Lan P,Tonomura N,Shimizu A,et al.Reconstitution of a functional human immune system in immunodeficient mice through combined human fetal thymus/liver and CD34+ cell transplantation[J].Blood,2006,108(2):487-492.
[7] Rongvaux A,Takizawa H,Strowig T,et al.Human hemato-lymphoid system mice:Current use and future potential for medicine[J].Annu Rev Immunol,2013,31:635-674.
[8] Ishikawa F,Yasukawa M,Lyons B,et al.Development of functional human blood and immune systems in nod/scid/il2 receptor {gamma} chain(null) mice[J].Blood,2005,106(5):1565-1573.
[9] Hu Z,Van Rooijen N,Yang YG.Macrophages prevent human red blood cell reconstitution in immunodeficient mice[J].Blood,2011,118(22):5938-5946.
[10] Amaladoss A,Chen Q,Liu M,et al.De novo generated human red blood cells in humanized mice support plasmodium falciparum infection[J].PLoS One,2015,10(6):e0129825.
[11] Hu Z,Van Rooijen N,Yang YG.Macrophages prevent human red blood cell reconstitution in immunodeficient mice[J].Blood,2011,118(22):5938-5946.
[12] Wang J,Hayashi Y,Yokota A,et al.Expansion of epor-negative macrophages besides erythroblasts by elevated epor signaling in erythrocytosis mouse models[J].Haematologica,2018,103(1):40-50.
[13] Oldenborg PA,Zheleznyak A,Fang YF,et al.Role of CD47 as a marker of self on red blood cells[J].Science,2000,288(5473):2051-2054.
[14] Ide K,Wang H,Tahara H,et al.Role for CD47-SIRPalpha signaling in xenograft rejection by macrophages[J].Proc Natl Acad Sci USA,2007,104(12):5062-5066.
[15] Kwong LS,Brown MH,Barclay AN,et al.Signal-regulatory protein alpha from the nod mouse binds human CD47 with an exceptionally high affinity-implications for engraftment of human cells[J].Immunology,2014,143(1):61-67.
[16] Hudson KE,deWolski K,Kapp LM,et al.Antibodies to senescent antigen and C3 are not required for normal red blood cell lifespan in a murine model[J].Front Immunol,2017,8:1425.
[17] Baxter AG,Cooke A.Complement lytic activity has no role in the pathogenesis of autoimmune diabetes in nod mice[J].Diabetes,1993,42(11):1574-1578.
[18] Chen B,Fan W,Zou J,et al.Complement depletion improves human red blood cell reconstitution in immunodeficient mice[J].Stem Cell Rep,2017,9(4):1034-1042.
[19] Giarratana MC,Kobari L,Lapillonne H,et al.Ex vivo generation of fully mature human red blood cells from hematopoietic stem cells[J].Nat Biotechnol,2005,23(1):69-74.
[20] Stevenson LM,Jones DG.Cross-reactivity amongst recombinant haematopoietic cytokines from different species for sheep bone-marrow eosinophils[J].J Comp Pathol,1994,111(1):99-106.
[21] Ji P,Murata-Hori M,Lodish HF.Formation of mammalian erythrocytes:chromatin condensation and enucleation[J].Trends Cell Biol,2011,21(7):409-415.
[22] Chen Q,Khoury M,Chen J.Expression of human cytokines dramatically improves reconstitution of specific human-blood lineage cells in humanized mice[J].Proc Natl Acad Sci USA,2009,106(51):21783-21788.
[23] Orkin SH,Zon LI.Hematopoiesis:an evolving paradigm for stem cell biology[J].Cell,2008,132(4):631-644.
[24] Cosgun KN,Rahmig S,Mende N,et al.Kit regulates HSC engraftment across the human-mouse species barrier[J].Cell Stem Cell,2014,15(2):227-238.
[25] Yurino A,Takenaka K,Yamauchi T,et al.Enhanced reconstitution of human erythropoiesis and thrombopoiesis in an immunodeficient mouse model with kit(wv) mutations[J].Stem Cell Rep,2016,7(3):425-438.
[26] Fiorini C,Abdulhay NJ,McFarland SK,et al.Developmentally-faithful and effective human erythropoiesis in immunodeficient and kit mutant mice[J].Am J Hematol,2017,92(9):E513-E519.
[27] Chen Q,Amaladoss A,Ye W,et al.Human natural killer cells control plasmodium falciparum infection by eliminating infected red blood cells[J].Proc Natl Acad Sci,2014,111(4):1479-1484.
[28] Xu Y,Wang S,Shen M,et al.hGH promotes megakaryocyte differentiation and exerts a complementary effect with c-Mplligands on thrombopoiesis[J].Blood,2014,123(14):2250-2260.
[29] Goodnough LT,Skikne B,Brugnara C.Erythropoietin,iron,and erythropoiesis[J].Blood,2000,96(3):823-833.
[30] Da Costa L,Galimand J,Fenneteau O,et al.Hereditary spherocytosis,elliptocytosis,and other red cell membrane disorders[J].Blood Rev,2013,27(4):167-178.
[31] Lu SJ,Feng Q,Park JS,et al.Biologic properties and enucleation of red blood cells from human embryonic stem cells[J].Blood,2008,112(12):4475-4484.
[32] Sugimura R,Jha DK,Han A,et al.Haematopoietic stem and progenitor cells from human pluripotent stem cells[J].Nature,2017,545(7655):432-438.
[33] Suzuki K,Tsunekawa Y,Hernandez-Benitez R,et al.In vivo genome editing via crispr/cas9 mediated homology-independent targeted integration[J].Nature,2016,540(7631):144-149.
[34] Kaushansky A,Mikolajczak SA,Vignali M,et al.Of men in mice:The success and promise of humanized mouse models for human malaria parasite infections[J].Cell Microbiol,2014,16(5):602-611.
[35] Dinga JN,Gamua SD,Ghogomu SM,et al.Preclinical efficacy and immunogenicity assessment to show that a chimeric plasmodium falciparum ub05-09 antigen could be a malaria vaccine candidate[J].Parasite Immunol,2018,40(3):e12514.
[36] Moreno A,Perignon JL,Morosan S,et al.Plasmodium falciparum-infected mice:More than a tour de force[J].Trends Parasitol,2007,23(6):254-259. |
