关键词: 抗心脂, 血液, 抗体, 抗核, 血液, 流产, 自然, 诊断, 酶联免疫吸附测定, 方法

Abstract: Objective To explore the relations of recurrent spontaneous abortion (RSA) with anticardiolipin antibody (ACA) and antinuclear antibody (ANA). Methods The levels of ACA and ANA in serum of 98 RSA patients and 40 normal women were detected by ELISA. Results The positive rate of ACA in RSA patients (32.7%) was obviously higher than normal wowen (5.0%) (P<0.01);there was no difference of the positive rate of ACA in statistics between early and late RSA, as well as between 2 times and more than 2 times abortions of RSA patients(P>0.05); the positive rates of IgG and IgM were higher among IgM,IgG and IgA of ACA, only 4 RSA patients were positive in all, the positive rate of middle and high level of ACA was 37.5%(11/32), the rest were low levels. The positive rate of ANA in RSA patients (17.3%) was obviously higher than that in normal women (2.5%) (P<0.05). Conclusion ACA and ANA are related with RSA, and may be regarded as a immunological assistant diagnostic index.

Key words: blood, antibodies, antinuclear, blood, abortion, spontaneous, diagnosis, enzyme-linked immunosorbent assay, methods