关键词:  , 终末期肾病, 抑郁, 生存质量

Abstract: Abstract:Objective To analyze the effect factors of   depression occurrence in  patients with end-stage renal disease,and to elucida
te the  impact of depression on life quality of patients with end-stage renal disease. Methods 186  patients with end-stage renal disease were
 divided into depression and non-depression patients according to BECK depression questionary.Then the Kidney Disease Quality of Life Short For
m（KDQOL-SF）of patients were measured and the results were analyzed. Results In all 186 patients,138 (74.2%) were depressed,including 26  cases of marginal depression,72 cases of   moderate depression,37 cases of  severe  depression and 3  cases of  critical depression.The incid
ence of depression was not correlated with gender or marital status (P>0.05),but it was correlated with age,occupational status,educational level,economic status,duration of dialysis,and type of medicare (P<0.05).There were significant differences in symptom/problems,effects of kidney disease on daily life(EKD),work status(WS),cognitive function(CF),quality of social interaction(QSI),sexual function(SexF) and sleep between  depr
ession and non-depression patients (P<0.05),while there were no significant differences in burden of kindey disease(BKD),social support(SOS),dialysis staff encouragement(DSE) or patient satisfaction(PS) between two kinds of patients(P>0.05).Depression was correlated with pain,genera
l health preperceptions(GH),emotion well-being(EUB),role linitations caused by emotional health problems(RE),social function(SocF),energy /fatigue,and changes in health(GH) and general health scales (P<0.05),but depression  wasn’t correlated with   physical functioning(DF) or role limitations caused by physical health problems (RP)(P>0.05).  Conclusion 14 dimensionalities of survival quality (symptom/ problems,EKD,WS,CF,QSI,SexF,sleep,pain,GH
,EWB,RE,SocF,energy/fatigue,change in health and general health scales) are positively  correlated with depression occurrence in  patients with end-stage renal disease.

Key words: end-stage renal disease, depression, survival quality