关键词: 过敏性紫癜, 儿童, 肺炎支原体抗体

Abstract:

Objective: To detect the Mycoplasma pneumoniae (MP)antibody in the children with Henoch-Schonlein purpura(HSP),and to clarify the correlation between MP infection and HSP in the children.Methods: A total of 323 cases of hospitalized children with HSP in the same age group and period and in line with the diagnosis criteria. 52 cases of arrhythmia patients without a recent history of infection,247 cases of acute bronchitis and 122 cases of children with bronchopneumonia were selected as HSP, arrhythmia, acute bronchitis and bronchopneumonia groups.According to the standard set,the HSP patients were divided into refractory HSP group and general HSP group.Pssive agglutination method was to detect the MP antibody in serum of the children in various groups and statistical analysis was performed.Results: The MP antibodies in 281 children in HSP group were detected and they were positive in 153 cases (54.4%); the MP antibodies in 52 cases in arrhythmia group were detected and they were positive in 17 cases (32.7%);the MP antibodies in 247 cases in acute bronchitis group was detected and they were positive in 146 cases (59.1%); the MP antibodies in 122 cases in bronchopneumonia group were detected and they were positive in 46 cases (37.7%).Compared with arrhythmia and bronchiopneumonia groups,the positive rate of MP antibodies in HSP group was significantly increased(P<0.05);compared with acute bronchitis group,the positive rate of MP antibodies in HSP group had no significant difference(P>0.05).Compared with general HSP group,the positive rate of MP antibodies in refractory HSP group was significantly increased (P<0.05).Conclusion: The positive rate of MP antibodies in the children with HSP is increased;MP antibodies may make the HSP complicated in the HSP children.

Key words: children, Henoch-Schonlein purpura, Mycoplasma pneumoniae antibody