| [1] Christopher AL,Tamotsu Y,Sharon AT.The autophagosome:origins unknown,biogenesis complex[J].Nat Rev Mol Cell Biol,2013,14(12):759-774.[2] Mizushima N,Levine B,Cuervo AM,et al.Autophagy fights disease through cellular self-digestion[J].Nature,2008,451(7182):1069-1075.[3] Vijg J.The role of DNA damage and repair in aging:new approaches to an old problem [J].Mech Ageing Dev,2008,129(7):498-502.[4] Choi AMK,Ryter,SW,Levine B.Autophagy in human health and disease [J].New Engl J Med,2013,368 (7):651-662.[5] Kaminskyy V,Zhivotovsky B.Proteases in autophagy [J].Biochim Biophys Acta,2012,1824(1):44-50.[6] Rubinsztein DC,Marifio G,Kroemer G.Autophagy and aging [J].Cell,2011,146(5):682-695.[7] Yu L,Strandberg L,Lenardo MJ.The selectivity of autophagy and its role in cell death and survival[J].Autophagy,2008,4(5):567-573.[8] Ravikumar B,Sarkar S,Davies JE,et al.Regulation of mammalian autophagy in physiology and pathophysiology[J].Physiol Rev,2010,90 (4):1383-1435.[9] Tang ZM,Lin MG,Stowe TR,et al.Autophagy promotes primary ciliogenesis by removing OFD1 from centriolar satellites[J].Nature,2013,502(7470) :254-257.[10] Weichhart T.Mammalian target of rapamycin:a signaling kinase for every aspect of cellular life[J].Methods Mol Biol,2012,821:1-14.[11] Inoki K,Kim J,Guan KL.AMPK and mTOR in cellular energy homeostasis and drug targets[J].Annu Rev Pharmacol Toxicol,2012,52 :381-400.[12] Maiuri MC1,Galluzzi L,Morselli E,et al.Autophagy regulation by p53[J].Cell Biol,2010,22(2):181-185.[13] Tasdemir E,Maiuri MC,Galluzzi L,et al.Regulation of autophagy by cytoplasmic p53[J].Nat Cell Biol,2008,10(6):676-687.[14] Otomo C,Metlagel Z,Takaesu G,et al.Structure of the human ATG12~ATG5 conjugate required for LC3 lipidation in autophagy[J].Nat Struct Mol Biol,2013,20(1):59-66.[15] Shoji-Kawata S,Sumpter R,Leveno M,et al.Identification of a candidate therapeutic autophagy-inducing peptide[J].Nature,2013,494 (7436):201-206.[16] Li WB,Struijk RB,Ma Q,et al.The histone H4 lysine 16 acetyltransferase hMOF regulates the outcome of autophagy[J].Nature,2013,500(7436):468-471.[17] Jones SA,Mills KH,Harris J.Autophagy and inflammatory diseases[J].Immunol Cell Biol,2013,91(3):250-258.[18] Melendez A,Talloczy Z,Seaman M, et al.Autophagy genes are essential for dauer development and life-span extension in C.elegans[J].Science,2003,301 (5638):1387-1391.[19] 王慧俐.饮食限制诱导细胞自噬及其对老龄大鼠寿命的影响[D].太原:山西医科大学,2010.[20] Mariño G1,Ugalde AP,Salvador-Montoliu N,et al.Premature aging in mice activates a systemic metabolic response involving autophagy induction[J].Hum Mol Genet,2008,17(14):2196-2211.[21] 徐秋林.自噬在心肌缺血-再灌注损伤中的不同作用[D].广州:南方医科大学,2012.[22] Oehme I,Linke JP,Böck BC,et al.Histone deacetylase 10 promotes autophagy-mediated cell survival[J].Proc Natl Acad Sci USA,2013,110(28):E2592-2601.[23] Mathew R,Karp CM,Beaudoin B,et al.Autophagy suppresses tu-morigenesis through elimination of p62[J].Cell,2009,137(6):1062-1075.[24] Choi KS.Autophagy and cancer[J].Exp Mol Med,2012,44(2):109-120.[25] Wang WJ, Wang Y,Chen HZ,et al.Orphan nuclear receptor TR3 acts in autophagic cell death via mitochondrial signaling pathway[J].Nat Chem Biol,2014,10(2):133-140.[26] Yang S,Wang X,Gontino G,et al.Pan creatic cancers require antophagy for tumor growth[J].Genes Dev,2011,25(7):717-729.[27] Daniel PH,Nicholas GC,Shailaja H,et al.TRPM3 and miR-204 establish a regulatory circuit that controls oncogenic autophagy in clear cell renal cell carcinoma[J].Cancer Cell,2014,26(5):738-753.[28] Thorburn J,Andrysik Z,Staskiewicz L,et al.Autophagy controls the kinetics and extent of mitochondrial apoptosis by regulating PUMA levels[J].Cell Rep,2014,7(1):45-52.[29] 胡 惠,王宗鼎,李可洲,等.氟尿嘧啶联合丝裂霉素经改变自噬作用减少胆管癌细胞株QBC939的细胞衰老并促进凋亡[J].第三军医大学学报,2013,35(18):1915-1920.[30] Gump JM,Staskiewicz L,Morgan MJ,et al.Autophagy variation within a cell population determines cell fate through selective degradation of Fap-1[J].Nat Cell Biol,2014,16(1):47-54. |
