Journal of Jilin University Medicine Edition ›› 2017, Vol. 43 ›› Issue (01): 164-169.doi: 10.13481/j.1671-587x.20170133

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Comparison of application effects bwtween contrast-enhanced ultrasound and conventional ultrasound in liver neoplasm biopsy

LIN Yuanqiang1, ZHANG Genmao1, SUI Guoqing1, GUO Li2, LI Hequn1, TANG Lidong1, WANG Hui1   

  1. 1. Department of Ultrasound, China-Japan Union Hospital, Jilin University, Changchun 130033, China;
    2. Department of Material Supply, China-Japan Union Hospital, Jilin University, Changchun 130033, China
  • Received:2016-10-19 Online:2017-01-28 Published:2017-02-08

Abstract:

Objective: To investigate the clinical application value of contrast-enhanced ultrasound in liver neoplasm biopsy and the related factors influencing the accuracy rate of biopsy,and to provide the useful evidence for early diagnosis of liver neoplasm.Methods: A total of 71 patients with liver neoplasms(73 neoplasms) were selected and divided into conventional ultrasound group (underwent biopsy guided by conventional ultrasound) (45 neoplasms) and contrast-enhanced ultrasound group(underwent biopsy guided by contrast-enhanced ultrasound) (28 neoplasms).The biopsy results were compared with the pathologic results.At the same time,the relationships between the accuracy rate of puncture and the characteristics of neoplasms were analyzed.Results: The accuracy rates of biopsy in conventional ultrasound group was 73.33%,and 92.86% in contrast-enhanced ultrasound group;there was significant difference between two groups(χ2=4.245,P<0.05).In conventional ultrasound group,the accuracy rate of 2-4 cm tumor was higher than that of 0-2 cm tumor(χ2=11.54,P<0.05);the accuracy rate of tumor with puncture depth < 5 cm was higher than that of tumor with puncture depth>5 cm (χ2=16.67,P<0.05);the accuracy rate of homogenous tumor was higher than that of inhomogenous tumor(χ2=9.66,P<0.05); the accuracy rate of clear margin tumor was higher than that of vague margin tumor(χ2=13.31,P<0.05);the accuracy rate of level Ⅱ-Ⅳ tumor was higher than that of level 0-Ⅰ tumor(χ2=9.82,P<0.05). The accuracy rates of tumor with puncture depth>5 cm and inhomogenous tumor in contrast-enhanced ultrasound group were higher than those in conventrional ultrasound group(P<0.05).Conclusion: Contrast-enhanced ultrasound can obviously increase the accuracy rate of liver neoplasm biopsy. Conventional ultrasound gets the low accuracy rates of liver neoplasm biopsy,especially for the tumor with diameter < 2 cm, inhomogeneous echoes (with liquefaction or not),vague margin,level 0-Ⅰ blood flow classification,and puncture depth >5 cm,suggesting contrast-enhanced ultrasound should be performed.

Key words: contrast-enhanced ultrasound, puncture, biopsy, ultrasonic guidance, liver neoplasms

CLC Number: 

  • R445.1