[1] 潘竞锵,刘广南,刘惠纯,等.茵陈蒿对小鼠血糖、血脂的影响[J].中药材,1998, 21(8):408-411. [2] 潘竞锵,韩超,刘惠纯,等.茵陈蒿汤对正常和多种糖尿病模型动物血糖的影响[J].中药材,2001,24(2):128-131. [3] 袁效涵,石鹤峰,韩伟峰.加味茵陈蒿汤治疗2型糖尿病40例[J].中医研究,2007,20(2):43-44. [4] GENG JN,YU XY,LIU CY,et al. Herba artemisiae capillaris extract prevents the development of streptozotocin-induced diabetic nephropathy of rat[J].Evid Based Complement Alternat Med,2018, 2018:5180165. [5] 孙成博,孙波,刘春禹,等.茵陈提取物对糖尿病大鼠肾组织miRNAs表达谱的影响及其肾脏保护作用[J]. 吉林大学学报:医学版,2018,44(3):493-498. [6] MAEHAMA T,DIXON J E.The tumor suppressor,PTEN/MMAC1,dephosphorylates the lipid second messenger,phosphatidylinositol 3,4,5-trisphosphate[J].J Biol Chem, 1998, 273(22):13375-13378. [7] 刘伦华,楼丽广.PTEN功能调节的研究进展[J].中国药理学通报,2005,21(7):778-781. [8] HADDADI N,LIN Y,TRAVIS G,et al.PTEN/PTENP1:Regulating the regulator of RTK-dependent PI3K/Akt signalling,new targets for cancer therapy[J].Mol Cancer, 2018, 17(1):37. [9] LEE YJ,HAN HJ.Troglitazone ameliorates high glucose-induced EMT and dysfunction of SGLTs through PI3K/Akt, GSK-3β, Snail1, and β-catenin in renal proximal tubule cells[J].Am J Physiol Renal Physiol,2010,298(5):F1263-F1275. [10] HAO J,LIU S,ZHAO S,et al.PI3K/Akt pathway mediates high glucose-induced lipogenesis and extracellular matrix accumulation in HKC cells through regulation of SREBP-1 and TGF-β1[J].Histochem Cell Biol,2011,135(2):173-181. [11] WANG XM,YAO M,LIU SX,et al.Interplay between the Notch and PI3K/Akt pathways in high glucose-induced podocyte apoptosis[J].Am J Physiol Renal Physiol,2014,306(2):F205-F213. [12] LI X Y,WANG SS,HAN Z,et al.Triptolide restores autophagy to alleviate diabetic renal fibrosis through the miR-141-3p/PTEN/Akt/mTOR pathway[J].Mol Ther Nucleic Acids,2017,9:48-56. [13] WANG H,FENG Z,XIE J,et al.Podocyte-specific knockin of PTEN protects kidney from hyperglycemia[J].Am J Physiol Renal Physiol,2018,314(6):F1096-F1107. [14] SUN J,LI ZP,ZHANG RQ,et al.Repression of miR-217 protects against high glucose-induced podocyte injury and insulin resistance by restoring PTEN-mediated autophagy pathway[J].Biochem Biophys Res Commun,2017,483(1):318-324. [15] 邢玲玲,傅淑霞,杨林,等.PTEN在糖尿病肾病患者足细胞损伤中的作用[J].临床与实验病理学杂志,2014,30(12):1375-1378. [16] MAHIMAINATHAN L,DAS F,VENKATESAN B,et al. Mesangial cell hypertrophy by high glucose is mediated by downregulation of the tumor suppressor PTEN[J].Diabetes,2006,55(7):2115-2125. [17] CAMPION CG,SANCHEZ-FERRAS O,BATCHU SN.Potential role of serum and urinary biomarkers in diagnosis and prognosis of diabetic nephropathy[J].Can J Kidney Health Dis,2017,4:2054358117705371. [18] 王圆圆,刘瑞霞,郭兵,等.大鼠肾组织PETN表达下调在糖尿病肾病发展中的作用[J].生理学报,2011,63(4):325-332. [19] 程悦,王代红,张耀全,等.PTEN编码蛋白对TGF-β1刺激大鼠肾成纤维细胞分泌Col Ⅳ、FN的抑制作用[J].解放军医学杂志,2007,32(7):719-721. [20] HLOBILKOVÁ A,KNILLOVÁ J,BÁRTEK J,et al.The mechanism of action of the tumour suppressor gene PTEN[J].Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub, 2003, 147(1):19-25. |