不同肝背景下原发性肝癌超声造影灌注特征的定量分析

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Quantitative analysis of perfusion features of primary hepatic carcinoma in different hepatic background using contrast-enhanced ultrasound

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doi:10.13481/j.1671-587x.20160134

Abstract:

Objective: To investigate the contrast-enhanced ultrasound features of primary hepatic carcinoma in normal liver,cirrhosis liver and fatty liver background,and to quantitatively analyze the blood flow perfusion features of tumors in different hepatic background. Methods: One hundred and thirty-seven patients with primary hepatic carcinoma including one hundred and thirty-seven primary focuses were selected.The patients were divided into normal liver group(n=45),cirrhotic liver group(n=51)and fatty liver group(n=41)according the different liver background.The enhancement features of focuses in different hepatic background were observed.The perfusion parameters including rise time,time to peak,maximum of intensity,gradient and area under the curve were analyzed by time-intensity curve. Results: All leisions of 137 patients presented hyperehcoic enhancement in arterial phase and majority of the lesions presented typically as fast in fast out.6.7% of leisions in normal liver group and 41.2% of the leisions in cirrhotic hepatic group presented equivalent even hyperechoic enhancement in the portal and delayed phase as fast in and slow out. The perfusion features of tumors such as rise time,time to peak,maximum of intensity,gradient and area under the curve in any two hepatic background groups had no significant differences (P>0.05). Conclusion: There are differences in contrast-enhanced ultrasound features of primary hepatic carcinoma with different hepatic background,but there is no significant differences in the perfusion parameters in three groups. The time-intensity curve can analysze the perfusion parameters of contrast-enhanced ultrasound of primary hepatic carcinoma objectively,which is helpful for differential diagnosis.

Key words: contrast-enhanced ultrasound, liver background, fatty liver, hepatic cirrhosis, liver neoplasms, time-intensity curve

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R445.1

ZHANG Lili, GU Jinhua, QI Yunfeng, ZHAO Lirong. Quantitative analysis of perfusion features of primary hepatic carcinoma in different hepatic background using contrast-enhanced ultrasound[J].Journal of Jilin University Medicine Edition, 2016, 42(01): 164-167.

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