Journal of Jilin University(Medicine Edition) ›› 2021, Vol. 47 ›› Issue (3): 637-643.doi: 10.13481/j.1671-587X.20210313
• Research in basic medicine • Previous Articles Next Articles
Chunqing MU1,Lei ZHOU1,Nan ZHAO1,Hong WANG1,Zhi LI2()
Received:
2020-08-19
Online:
2021-05-28
Published:
2021-05-28
Contact:
Zhi LI
E-mail:cljlizhi@163.com
CLC Number:
Chunqing MU, Lei ZHOU, Nan ZHAO, Hong WANG, Zhi LI. Effect of metformin on proliferation of lung cancer A549 cells through PI3K/AKT/GSK3β signaling pathway[J].Journal of Jilin University(Medicine Edition), 2021, 47(3): 637-643.
Tab. 1
Proliferation rates of A549 cells in various groups at different time points (n=3,x±s, η/%)"
Group | Proliferation rate of A549 cells | |||
---|---|---|---|---|
(t/d) 24 | 48 | 72 | ||
Control | 100.00±0.00 | 100.00±0.00 | 100.00±0.00 | |
Metformin (mmol·L-1) | ||||
1 | 96.95±1.88* | 91.09±0.41* | 91.54±4.25* | |
2 | 91.80±1.23* | 87.87±3.46* | 81.91±1.00* | |
4 | 87.01±8.19* | 84.13±1.06* | 76.24±0.22* | |
8 | 84.46±1.61* | 74.79±0.41* | 60.32±2.98* | |
16 | 81.90±6.79* | 67.20±2.00* | 52.99±2.13* | |
32 | 79.60±1.37* | 57.04±3.77* | 22.68±0.30* |
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