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Preparation and degradation of porous β-tricalcium phosphate bioceramic for bone imitaion
MA Yun-hai, SHANG Wen-bo, FAN Xue-ying, GAO Zhi-hui, TONG Jin, YAN Zhi-feng, CHANG Zhi-yong
吉林大学学报(工学版). 2015, 45 (4):
1367-1374.
DOI: 10.13229/j.cnki.jdxbgxb201504049
In this study, porous β-tricalcium Phosphate (β-TCP) bioceramic is prepared by the following steps. First, calcium nitrate and 2-phosphonic acid-1,2,4-tricarboxylic acid (PBTC) are used as raw materials to synthesize the precursor; second, β-TCP power was prepared by dehydration concentration and high temperature sintering; third, β-TCP power is taken as the matrix, stearic acid as porogen and PVA as binder to prepare the moudles by press molding; finally, β-TCP bioceramic is prepared by sintering of the moudles. The compositions of the β-TCP bioceramic are analyzed using X-ray diffraction analysis, scanning electron microscopy and EDX spectroscopy. Degradation experiments are carried out using the specimens with four levels of porogen, 15%, 20%, 25% and 30% respectively. Results show that the specimen with 30% of porogen has the best degradation performance. EDX analysis and scanning electron microscopy observation confirm the generation of hydroxyapatite materials on the surface of the β-TCP bioceramic.
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