In order to fully reveal the migration and transformation of the pesticide atrazine in natural water bodies we studied the characteristics of atrazine adsorption on the sediments influenced by a variety of environmental factors (such as pH, ionic strength, aeration rate, and temperature) via
the simulation by means of self\|designed natural water environment adsorption/desorption system experimental device based on 24 full factorial experimental design, and then employed the fixed effect model to analyze the contribution from the mathematical quantitative perspective about the main effects of various environmental factors and higherorder interaction effects to adsorption of atrazine on the sediments. It was found that the main effects of the four selected environmental factors (pH, ionic strength, aeration rate, and temperature) all have a significant impact (significance level of 005) to atrazine adsorption on the sediments, in which the aeration rate and the ionic strength significantly promote atrazine adsorption on sediments, while the temperature and pH significantly restrain atrazine adsorption on the sediments; the secondorder interaction of environmental factors which have a significant influence on the atrazine adsorption (significance level of 0.05) follows the order of temperature×pH=-73.53, aeration×pH=-59.03, temperature×ionic strength=33.19, and pH×ionic strength=27.55, and only the thirdorder interaction of aeration rate×temperature×pH is be significant (significance level of 0.05), which promotes the atrazine adsorption on sediments.