[1] Berndt A, Sundberg BA, Silva KA, et al. Phenotypic characterization of the KK/HlJ inbred mouse strain[J]. Vet Pathol, 2014, 51(4):846-857. [2] Chang GR, Wu YY, Chiu YS, et al. Long-term administration of rapamycin reduces adiposity, but impairs glucose tolerance in high-fat diet-fed KK/HlJ mice[J]. Basic Clin Pharmacol Toxicol, 2009, 105(3):188-198. [3] Lin YJ, Zhen YS. Rhein lysinate suppresses the growth of breast cancer cells and potentiates the inhibitory effect of Taxol in athymic mice[J]. Anticancer Drugs, 2009, 20(1):65-72. [4] Hu G, Liu J, Zhen YZ, et al. Rhein lysinate increases the median survival time of SAMP10 mice:protective role in the kidney[J]. Acta Pharmacol Sin, 2013, 34(4):515-521. [5] Wei J, Zhen YZ, Cui J, et al. Rhein lysinate decreases inflammation and adipose infiltration in KK/HlJ diabetic mice with non-alcoholic fatty liver disease[J]. Arch Pharm Res, 2016, 39(7):960-969. [6] Zhen YZ, Lin YJ, Li KJ, et al. Effects of rhein lysinate on D-galactose-induced aging mice[J]. Exp Ther Med, 2016, 11(1):303-308. [7] 周士胜,伦永志,李胜范. 2型糖尿病病因可能在肝脏[J]. 大连大学学报, 2008,29(3):89-91. [8] Iizuka Y, Kim H, Izawa T, et al. Protective effects of fish oil and pioglitazone on pancreatic tissue in obese KK mice with type 2 diabetes[J]. Prostaglandins Leukot Essent Fatty Acids, 2016, 115:53-59. [9] Muroyama K, Murosaki S, Yamamoto Y, et al. Anti-obesity effects of a mixture of thiamin, arginine, caffeine, and citric acid in non-insulin dependent diabetic KK mice[J]. J Nutr Sci Vitaminol, 2003, 49(1):56-63. [10] 高啸,彭旖旎,朱琳,等. 硫化氢对2型糖尿病大鼠肝脏胰岛素抵抗的影响[J]. 华中科技大学学报:医学版, 2016,45(5):490-495. [11] Wen L, Duffy A. Factors influencing the gut microbiota, inflammation, and type 2 diabetes[J]. J Nutr, 2017, 147(7):1468S-1475S. [12] Wei J, Zhen YZ, Cui J, et al. Rhein lysinate decreases inflammation and adipose infiltration in KK/HlJ diabetic mice with non-alcoholic fatty liver disease[J]. Arch Pharm Res, 2016, 39(7):960-969. [13] Wang X, Zhao L. Calycosin ameliorates diabetes-induced cognitive impairments in rats by reducing oxidative stress via the PI3K/Akt/GSK-3β signaling pathway[J]. Biochem Biophys Res Commun, 2016, 473(2):428-434. [14] Zhou L, Wang L, Yang B, et al. Protective effect of pretreatment with propofol against tumor necrosis factor-alpha-induced hepatic insulin resistance[J]. Exp Ther Med, 2015, 10(1):289-294. [15] Wang X, Wang M, Li H, et al. Upregulation of miR-497 induces hepatic insulin resistance in E3 rats with HFD-MetS by targeting insulin receptor[J]. Mol Cell Endocrinol, 2015, 416:57-69. |