[1] SYLAJA P N, PANDIAN J D, KAUL S,et al. Ischemic stroke profile, risk factors, and outcomes in india[J]. Stroke, 2019, 49(1):219-222. [2] YANG H J, XI X X, ZHAO B,et al.KLF4 protects brain microvascular endothelial cells from ischemic stroke induced apoptosis by transcriptionally activating MALAT1[J].Biochem Biophys Res Commun,2018,495(3):2376-2382. [3] MA Y, XIA X, CHENG J M,et al. Emodin inhibits inducible nitric oxide synthase in a rat model of craniocerebral explosive injury[J]. Neurochem Res, 2014, 39(9):1809-1816. [4] GUO H L, SHEN X R, XU Y,et al.Emodin prevents hypoxic-ischemic neuronal injury: Involvement of the activin A pathway[J].Neural Regen Res,2013,8(15):1360-1367. [5] 谭力,王联英,向海鹰,等.大黄素对脑缺血再灌注大鼠的保护作用及机制研究[J].中西医结合心脑血管病杂志,2010,8(9):1100-1101. [6] LONGA E Z, WEINSTEIN P R, CARLSON S,et al.Reversible middle cerebral artery occlusion without craniectomy in rats[J].Stroke,1989,20(1):84-91. [7] TALKE P, BICKLER P E. Effects of dexmedetomidine on hypoxia-evoked glutamate release and glutamate receptor activity in hippocampal slices[J]. Anesthesiology, 1996, 85(3):551-557. [8] BALAGANAPATHY P, BAIK S H, MALLILANKARAMAN K,et al.Interplay between Notch and p53 promotes neuronal cell death in ischemic stroke[J].J Cereb Blood Flow Metab,2018,38(10):1781-1795. [9] CHANG Q Y, LIN Y W, HSIEH C L.Acupuncture and neuroregeneration in ischemic stroke[J].Neural Regen Res,2018,13(4):573-583. [10] ZHAO T F, FU Y X, SUN H,et al.Ligustrazine suppresses neuron apoptosis via the Bax/Bcl-2 and caspase-3 pathway in PC12 cells and in rats with vascular dementia[J].IUBMB Life,2018,70(1):60-70. [11] WEN H L, WU Z, HU H D,et al.The anti-tumor effect of pachymic acid on osteosarcoma cells by inducing PTEN and Caspase 3/7-dependent apoptosis[J].J Nat Med,2018,72(1):57-63. [12] PANNEER SELVAM S, ROTH B M, NGANGA R,et al.Balance between senescence and apoptosis is regulated by telomere damage-induced association between p16 and caspase-3[J].J Biol Chem,2018,293(25):9784-9800. [13] DANIELE S, PIETROBONO D, COSTA B,et al.Bax activation blocks self-renewal and induces apoptosis of human glioblastoma stem cells[J].ACS Chem Neurosci,2018,9(1):85-99. [14] GUO X W, XIANG C X, ZHANG Z T,et al.Displacement of bax by BMF mediates STARD133’UTR-induced breast cancer cellsapoptosisin an miRNA-depedent manner[J].Mol Pharm,2018,15(1):63-71. [15] EDLICH F. BCL-2 proteins andapoptosis: Recent insights and unknowns[J].Biochem Biophys Res Commun,2018,500(1):26-34. [16] PEÑA-BLANCOA, GARCÍA-SÁEZ A J.Bax, Bak and beyond-mitochondrial performance in apoptosis[J].FEBS J,2018,285(3):416-431. [17] 张雯, 宋俊科, 杜冠华. 缺血再灌注损伤与细胞凋亡信号转导通路[J]. 中国药学杂志, 2015, 50(7):565-569. [18] PARK H, AHN S H, JUNG Y,et al.Leptin suppresses glutamate-induced? apoptosisthrough regulation of ERK1/2 signaling pathways in rat primary astrocytes[J].Cell Physiol Biochem,2017,44(6):2117-2128. [19] ELUKA-OKOLUDOH E, EWUNKEM A J, THORPE S,et al. Diepoxybutane-inducedapoptosis is mediated through the ERK1/2 pathway[J].Hum Exp Toxicol,2018,37(10):1080-1091. [20] 苏洲,田小军,王玉梅, 等.依达拉奉对急性缺血性脑卒中患者丝裂原活化蛋白激酶/细胞外调节蛋白激酶信号通路蛋白表达的影响[J].中华老年医学杂志,2018,37(12):1372-1375. [21] 罗素,荣晓凤,彭菲菲.大黄素对TNF-α诱导的成纤维样滑膜细胞株MH7A细胞ERK1/2和p38MAPK的影响[J].免疫学杂志,2017,33(2):113-117. [22] 王青,周联,董燕, 等.大黄素对HT-29细胞MAPKs信号通路活化及IL-8分泌的影响[J].现代生物医学进展,2011,11(11):2087-2089. [23] 杨海蕾,陈晨,屈秋民.社区脑卒中高危人群颈动脉粥样硬化与缺血性脑卒中的关系[J/OL].西安交通大学学报:医学版,2019[2019-11-18].http://kns.cnki.net/kcms/detail/61.1399.R.20191009.1055.006.htm |