锌缺乏症对慢性肾脏病发展的影响及其作用机制的研究进展

doi:10.13481/j.1671-587x.20180139

摘要/Abstract

摘要： 锌缺乏症能够通过降低金属蛋白酶及转录因子活性、诱导氧化应激和介导炎性反应等多种途径促进慢性肾脏病（CKD）的发生发展，并且在终末期肾病（ESRD）并发症的发生中发挥负性调节作用。本文作者就锌和锌缺乏症，锌缺乏症在糖尿病肾病、IgA肾病、儿童微小病变型肾病等CKD及皮肤瘙痒症、神经性厌食症等ESRD并发症中的影响机制做一综述，为临床积极纠正CKD患者锌缺乏症提供理论依据。

关键词: 慢性肾脏病, 糖尿病肾病, 锌缺乏症, 终末期肾病

中图分类号:

R589.9

陈良妹, 董晓明, 杨帆, 罗萍. 锌缺乏症对慢性肾脏病发展的影响及其作用机制的研究进展[J]. 吉林大学学报(医学版), 2018, 44(01): 195-199.

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锌缺乏症对慢性肾脏病发展的影响及其作用机制的研究进展

Research progressin effect and mechanism of zinc deficiency in development of chronic kidney disease

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