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• 基础研究 • 上一篇    下一篇

水通道蛋白亚型AQP1-9在雄性小鼠生殖系统mRNA的表达

赵 丹1,杜建时2,杨 柯1,杨宝学3,赵雪俭1   

  1. 1. 吉林大学基础医学院病理生理学教研室,吉林 长春130021;2. 吉林大学中日联谊医院血管外科,吉林 长春130031;3. 美国加利福尼亚大学旧金山医学院,美国 旧金山 CA94122
  • 收稿日期:2003-03-20 修回日期:1900-01-01 出版日期:2004-01-28 发布日期:2004-01-28

AQP1-9 mRNA expression of water channelin reproductive tract of male mouse

ZHAO Dan1, DU Jian-shi2,YANG Ke1, YANG Bao-xue3,ZHAO Xue-jian1   

  1. 1. Department of Pathophysiology,School of Basic Medical Sciences,Jilin University,Changchun130021,China;2. Department of Vascular Surgery,China-Japan Union Hospital,Jilin University,Changchun130031,China;3. San Francisco Meclical College of California University,San Francisso CA94122,USA)
  • Received:2003-03-20 Revised:1900-01-01 Online:2004-01-28 Published:2004-01-28

摘要: 目的:明确AQP1-9在雄性小鼠生殖系统的分布与表达。方法:应用RT-PCR技术检测AQP1-9在雄性小鼠生殖系统不同器官的表达。结果:在成年雄性小鼠的生殖系统中,有多种水通道的表达,睾丸中有AQP3、5、7、8、9表达;附睾头中有AQP3、6、8表达;附睾尾有AQP3、5、6、7、8表达;输精管中有AQP1、2、3、4、5、6、7的表达。结论:小鼠生殖系统中多种水通道蛋白的表达提示AQP与生殖功能有密切关系。

关键词: 代谢, 睾丸, 代谢, 附睾, 代谢, 输精管, 代谢, 疾病模型, 动物

Abstract: Objective\ To determine the expression and distribution of aquaporin 1-9(AQP1-9)in male reproductive tract of mouse. Methods The expressions of AQP1-9 in various organs of male reproductive tract of mouse was determined using RT-PCR. Results The expression of AQP3,5,7,8,9 were present in mouse testis. AQP3,6,8 expression were found in capita epididymis and AQP3,5,6,7,8 in caudae epididymis. In vas deferens, the AQPs except for AQP8,9 were detected. Conclusions The different localization of AQP1-9 expression in male reproductive system of mouse shows that they may play an important role in physiological function of male reproductive system,especially for the maturation of sperm in different segments of male reproductive tract of mouse.

Key words: metabolism, tesis, metabolism, epididymis, metabolism, vas deferens, metabolism, disease models, animal

中图分类号: 

  • R339.21