Journal of Jilin University(Medicine Edition) ›› 2025, Vol. 51 ›› Issue (6): 1747-1754.doi: 10.13481/j.1671-587X.20250632

• Review • Previous Articles    

Research progress in treatment principles for endometrial cancer and its postoperative and postoperative recurrent radiotherapy

Teng LIU,Ning ZHANG,Mingyuan HE(),Guanghui CHENG()   

  1. Department of Radiation Oncology,China-Japan Union Hospital,Jilin University,Changchun 130033,China
  • Received:2025-03-12 Accepted:2025-05-15 Online:2025-11-28 Published:2025-12-15
  • Contact: Mingyuan HE,Guanghui CHENG E-mail:hemingyuan@jlu.edu.cn;chenggh@jlu.edu.cn

Abstract:

Endometrial cancer is one of the common malignant tumors of the female reproductive system. Its incidence rate in China is second only to cervical cancer, posing a serious threat to women’s life and health, and the onset shows a trend of affecting younger individuals. Currently, the primary treatment for endometrial cancer is surgical intervention, and some postoperative patients and those with postoperative recurrence require adjuvant radiotherapy. Pelvic external beam radiotherapy(EBRT) and vaginal brachytherapy(VBT) are two modalities of postoperative radiotherapy. The appropriate postoperative radiotherapy approach should be selected based on individual conditions and guideline recommendations. Most patients can achieve satisfactory treatment outcomes through surgery and postoperative adjuvant radiotherapy. However, the specific indications for postoperative radiotherapy in endometrial cancer patients and the radiotherapy principles for those with postoperative recurrence are relatively complex, and recommendations for radiotherapy modalities in postoperative patients vary slightly across different guidelines. This article reviews the treatment principles for endometrial cancer patients in recent years, as well as the indications for postoperative and post operative recurrent radiotherapy and the radiotherapy techniques, aiming to provide a reference for radiotherapy in the endometrial cancer patients.

Key words: Endometrial cancer, Therapy principles, Reproductive system, Radiotherapy, Indication

CLC Number: 

  • R737.33