Journal of Jilin University Medicine Edition ›› 2015, Vol. 41 ›› Issue (05): 1041-1043.doi: 10.13481/j.1671-587x.20150533

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MRI performance of central pontine myelinolysis and its application in diagnosis

MA Yongjin1,2, LIU Shuo2, LI Tong2, NIU Meng2, DING Jun2, AN Liying2   

  1. 1. Department of Radiology, Affiliated Hospital, Jilin Medical College, Jilin 132013, China;
    2. Department of Radiology, China-Japan Union Hospital, Jilin University, Changchun 130033, China
  • Received:2014-12-17 Published:2015-09-29

Abstract:

Objective To investigate the MRI performance of five cases of central pontine myelinolysis (CPM),and to clarify the application of MRI in the diagnosis of CPM in order to improve its diagnosis level. Methods The main history and clinical manifestations of 5 patients with CPM were collected.The Philip Achieva 3.0T superconducting MR was used to detect the sequences of T1WI,T2WI,Fiair and diffusion-weighted imaging(DWI) from the bottom of posterior fossa to parietal. Results The MRI performance of CPM as follows:the location of CPM was in the center of the pons,and the transverse pontine fibers were most severely affected with the sparing of descending corticospinal tracts,and there was no mass or edema;the lesion appeared hypointense on T1 weighted image and hyperintense or slightly hyperintense on T2 weighted image and T2 Flair image,hyperintense or isointense on DWI image,and surrounding mild enhancement or no enhancement after enhancement scan.The lesion showed "convex" glyph,chestnut or patchy;few pons exostructure was involved such as basal ganglia,cortex,and cerebellum structure. Conclusion The MRI performance of CPM has its characteristics,and MRI images could be used in early diagnosis of CPM.

Key words: central pontine myelinolysis, myelinolysis, magnetic resonance imaging

CLC Number: 

  • R445.2