Abstract:

Objective: To investigate the infection status and influencing factors of hepatitis E virus infection among different occupational populations in Xinjiang region, and to provide a available evidence for control of hepatitis E. Methods: A randomly sampling survey was carried out in the population of public health practitioners, the serum IgG antibodies against hepatitis E virus in 1 720 samples were tested by indirect enzyme-linked immunosorbent assay, and the experimental data was analyzed with SPSS 19.0 software;the differences of infection rates between genders, ages and occupations were analyzed. Results: Among 1 720 subjects,440 persons were anti-HEV IgG positive,and the total positive rate was 25.58%; the positive rate of males (27.99%) was higher than that of females (23.35%), and the IgG positive rate was increased along with the age;there were significant differences of the anti-HEV-IgG antibody positive rates between the populations with different ages(χ²=118.262,P=0.000).There was a statistically significant difference of infection rate of hepatitis E between different occupational populations(χ²=98.262,P=0.000), the slaughterman had the highest positive rate (81.53%), followed by the livestock and meat salesperson (79.37%), food service population (30%), supermarket population (11.21%) and others (9.03%). Conclusion: The hepatitis E infection rate is high among the public health practitioners in Xinjiang region, and occupation, age and gender are the major influencing factors of hepatitis E infection rate.

Key words: hepatitis E virus, public health, serosurvey, enzyme-linked immunosorbent assay