The cervical cancer HeLa cells were divided into control group（given no treatment） and different concentrations （10， 20，and 40 μmol?L^－1） of CAR groups（given different concerntrations of CAR）. CCK-8 method was used to detect the viabilities of the cervical cancer HeLa cells in various groups at 24， 48，and 72 h after treatment； the colony formation experiment was used to detect the clone formation number of the cervical cancer HeLa cells in various groups；and the apoptotic morphology of cervical cancer HeLa cells in various groups was observed by Hoechst33258 staining； Western blotting method was used to detect the expression levels of B-cell lymphoma-2（Bcl-2），Bcl-2 associated X protein（Bax），phosphorylated-phosphatidylinositol 3-kinase（p-PI3K），and phosphorylated-protein kinase B（p-AKT）proteins in the HeLa cells in various groups.

Compared with control group， the viabilities of the cervical cancer HeLa cells in different concentrations of CAR groups after treated for different time were decreased （24 h：P=0.011 8； 48 h：P=0.000 4； 72 h：P=0.002 2）；compared with control group， the clone formation number of HeLa cells in different concentrations of CAR groups was significantly decreased （P<0.01）；compared with control group， the apoptotic morphology of HeLa cells in different concentrations of CAR groups showed as nuclear aggregation， shrinkage or fragmentation； compared with control group， the expression levels of Bcl2， p-PI3K（P=0.011 8）， and p-AKT（P=0.034 9） proteins in the cervical cancer HeLa cells in different concentrations of CAR groups were significantly decresed， while the levels of Bax protein were increased， and the ratios of Bcl-2/Bax were decreased（P<0.01）.

CAR can induce the apoptosis and inhibit the proliferation of cervical cancer HeLa cells by regulating the PI3K/AKT signaling pathway.