Journal of Jilin University(Medicine Edition) ›› 2021, Vol. 47 ›› Issue (2): 469-476.doi: 10.13481/j.1671-587X.20210228
• Research in clinical medicine • Previous Articles Next Articles
Yangyang SONG1,Tingting LIN1,Qianyan HE2,Huanqiu LIU1(),Yanhua FENG1()
Received:
2020-05-22
Online:
2021-03-28
Published:
2021-03-25
Contact:
Huanqiu LIU,Yanhua FENG
E-mail:chunqiu2002@163.com;fengyanhua77@163.com
CLC Number:
Yangyang SONG,Tingting LIN,Qianyan HE,Huanqiu LIU,Yanhua FENG. Effect of ulinastatin pretreatment on postoperative recipients’ renal function in operation of donation after controllable cardiac death[J].Journal of Jilin University(Medicine Edition), 2021, 47(2): 469-476.
Tab. 1
Comparison of donor data among three groups"
Items | Age (year) | Gender [male,n(η/%] | BMI (kg·m-2) | MAP (P/mmHg) | HR (beat·min-1) | Na+ [cB/(mmol·L-1)] |
---|---|---|---|---|---|---|
Control | 49.53±6.94 | 22(73.3) | 23.56±2.23 | 99.10±8.31 | 92.43±8.42 | 140.65±6.95 |
U1 | 46.13±9.16 | 24(80.0) | 24.23±1.99 | 100.78±9.20 | 88.33±8.91 | 141.94±4.23 |
U2 | 45.33±11.63 | 22(73.3) | 23.55±1.70 | 99.54±7.43 | 89.10±11.38 | 142.17±10.30 |
χ2/F | 1.675 | 0.481 | 1.157 | 0.326 | 1.529 | 0.349 |
P | 0.193 | 0.786 | 0.319 | 0.723 | 0.222 | 0.706 |
Group | Serum creatinine [cB/ (mmol·L-1)] | Blood urea nitrogen [cB/ (mmol·L-1)] | CPR [Yes,n(η/%)] | Cause of death[n(η/%)] | ||
Trauma | Cerebral hemorrhage | Others | ||||
Control | 91.50(78.75,101.18) | 4.83(3.80,5.86) | 2(6.7) | 13(43.3) | 14(46.7) | 3 (10.0) |
U1 | 91.75(65.83,104.68) | 3.68(2.98,6.15) | 1(3.3) | 15(50.0) | 12(40.0) | 3 (10.0) |
U2 | 86.10(68.00,108.78) | 4.19(3.75,7.02) | 2(6.7) | 14(46.7) | 13(43.3) | 3 (10.0) |
χ2/F | 0.339 | 3.079 | — | — | ||
P | 0.844 | 0.214 | 0.999 | 0.996 |
Tab. 2
Comparison of recipient data among three groups"
Group | n | Gender [male,n(η/%] | Age (year) | BMI (kg·m-2) | Warm ischemia time (t/min) | Cold ischemia time (t/h) | Preoperative dialysis (year) | Operation time(t/min) | ||
---|---|---|---|---|---|---|---|---|---|---|
Control | 57 | 36(63.2) | 43.95±9.53 | 22.79±2.93 | 3.47±0.69 | 6.34±3.17 | 2.5(1.5,4.5) | 117.40±16.60 | ||
U1 | 59 | 37(62.7) | 42.08±11.36 | 22.4±2.76 | 3.53±0.48 | 7.12±3.28 | 2.0(1.0,3.0) | 119.68±17.41 | ||
U2 | 58 | 35(60.3) | 45.10±10.76 | 23.06±2.57 | 3.34±0.47 | 7.26±3.26 | 2.0(1.0,3.0) | 117.02±17.01 | ||
χ2/F | 0.112 | 1.212 | 0.821 | 1.786 | 1.355 | 3.378 | 0.418 | |||
P | 0.945 | 0.300 | 0.442 | 0.171 | 0.261 | 0.185 | 0.659 | |||
group | n | Dialysis methods[n(η/%)] | Renal arterial anastomosis[n(η/%)] | |||||||
Peritoneal dialysis | Hemodialysis | No | RA with IIA | RA with EIA | RA with IIA and EIA | |||||
Control | 57 | 5(8.8) | 50(87.7) | 2(3.5) | 2(3.5) | 55(96.5) | 0(0.0) | |||
U1 | 59 | 9(15.3) | 50(84.7) | 0(0.0) | 4(6.8) | 54(91.5) | 1(1.7) | |||
U2 | 58 | 10(17.2) | 47(81.0) | 1(1.7) | 5(8.6) | 52(89.7) | 1(1.7) | |||
χ2/F | — | — | ||||||||
P | 0.421 | 0.705 |
Tab. 3
MAP of recipients at different time points in three groups"
Group | n | MAP | |||
---|---|---|---|---|---|
Before anesthesia | After anesthesia | Renal artery opening | End of the surgery | ||
Control | 30 | 111.98±10.83 | 96.72±7.49 | 103.91±7.37 | 102.91±7.41 |
U1 | 59 | 111.12±10.85 | 96.53±7.96 | 102.73±7.77 | 102.79±7.83 |
U2 | 58 | 111.22±10.67 | 96.26±8.26 | 103.86±8.03 | 101.31±13.39 |
F | 0.110 | 0.049 | 0.438 | 0.469 | |
P | 0.896 | 0.952 | 0.646 | 0.626 |
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