吉林大学学报(医学版) ›› 2021, Vol. 47 ›› Issue (6): 1562-1569.doi: 10.13481/j.1671-587X.20210630

• 调查研究 • 上一篇    下一篇

广东省双相情感障碍患者危险行为的流行病学特征及其影响因素

陈东1,周娜2,张欣2,陶晓宇1,谭文艳3,林海程3,王诗镔3,赵赛赛4,高文会4,金丽娜4,于雅琴1,5()   

  1. 1.澳门科技大学医学院公共卫生系,澳门特别行政区 999078
    2.澳门科技大学药学院药理教研室,澳门特别行政区 999078
    3.广东省人民医院 广东省医学科学院 广东省精神卫生中心公共卫生事业科,广东 广州 510080
    4.吉林大学公共卫生学院流行病与卫生统计学教研室,吉林 长春 130021
    5.珠海科技学院健康学院预防医学教研室,广东 珠海 519041
  • 收稿日期:2021-03-11 出版日期:2021-11-28 发布日期:2021-12-14
  • 通讯作者: 于雅琴 E-mail:yuyaqin5540@163.com
  • 作者简介:陈 东(1979-),男,江苏省南通市人,在读博士研究生,主要从事精神障碍疾病分析和治疗方面的研究。
  • 基金资助:
    广东省卫健委医学科学技术研究基金项目(C2018026)

Epidemiological characteristics and influencing factors of risk behaviors of patients with bipolar disorder in Guangdong Province

Dong CHEN1,Na ZHOU2,Xin ZHANG2,Xiaoyu TAO1,Wenyan TAN3,Haicheng LIN3,Shibin WANG3,Saisai ZHAO4,Wenhui GAO4,Lina JIN4,Yaqin YU1,5()   

  1. 1.Department of Public Health,Faculty of Medicine,Macau University of Science and Technology,Macao Special Administrative Region 999078,China
    2.Department of Pharmacology,School of Pharmacy,Macau University of Science and Technology,Macao Special Administrative Region 999078,China
    3.Department of Public Health,Guangdong Mental Health Center,People’s Hospital,Guangdong Province,Guangzhou 510080,China
    4.Department of Epidemiology and Health Statistics,School of Public Health,Jilin University,Changchun 130021,China
    5.Department of Preventive Medicine,School of Health,Zhuhai University of Science and Technology,Zhuhai 519041,China
  • Received:2021-03-11 Online:2021-11-28 Published:2021-12-14
  • Contact: Yaqin YU E-mail:yuyaqin5540@163.com

摘要: 目的

探讨广东省双相情感障碍(BPD)患者的精神生活状态和危险行为等级等相关情况,阐明危险行为等级的相关影响因素,为制订相关的管理和治疗政策提供依据。

方法

采用多阶段抽样的方法,对2018年12月—2019年2月在广东省11个地级市中精神卫生机构(精神卫生专科机构和社区卫生服务中心)住院或管理的870例BPD患者行问卷调查和体格检查。根据危险行为评估等级将患者分为低危组(0~2级,n=798)和高危组(3~5级,n=72)。统计广东省BPD患者的一般人口学特征、临床特征和症状,采用多因素Logistic回归法分析BPD患者的危险行为影响因素。

结果

低危组患者平均年龄高于高危组(P<0.05);2组患者中男性构成比均较高,且高危组BPD患者中男性构成比高于低危组(P<0.05);低危组患者中已婚/同居者构成比较高(P<0.05),而高危组BPD患者中单身未婚者构成比较高(P<0.05)。高危组BPD患者幻觉、猜疑、喜怒无常、行为怪异、兴奋话多、伤人毁物和无故外走等临床症状的发生率均高于低危组(P<0.05);高危组患者中男性患者[OR(95%CI)=1.925(1.093~3.390)]、住院患者[OR(95%CI)=6.145(2.775~13.607)]、关锁[OR(95%CI)=3.178(1.523~6.629)]和用药不依从[OR(95%CI)=4.390(2.500~7.708)]构成比均高于低危组(P<0.05)。

结论

患者年龄、性别、来源和用药依从性是BPD患者发生危险行为的重要影响因素,较低的年龄、女性患者、社区居住患者和规律用药对降低BPD患者危险行为的发生起到一定的积极作用。应针对BPD患者制订综合、有效的综合管理模式,提升患者的生活质量。

关键词: 广东省, 双相情感障碍, 危险行为评估, 影响因素, Logistic回归

Abstract: Objective

To explore the mental life status and risk behavior levels of the patients with bipolar disorder(BPD) in Guangdong Province and clarify the influencing factors of risk behavior levels, and to provide the basis for the development of related management and treatment policies.

Methods

By using the multi-stage sampling method, 870 BPD patients who were hospitalized or managed in the mental health institutions (specialized mental health institutions and community health service centers) in 11 prefecture-level cities in Guangdong Province from December 2018 to February 2019 were investigated by questionnaire and physical examination.The patients were divided into low risk group (grade 0-2,n=798) and high risk group (grade 3-5,n=72) according to the risk behavior assessment grade. The general demographic characteristics, clinical characteristics,and symptoms of the BPD patients in Guangdong Province were statistically analyzed. The influencing factors of risk behaviors of the BPD patients were analyzed by multivariate Logistic regression.

Results

The avarage age of the BPD patients in low-risk group was higher than that in high-risk group (P<0.05). The composition ratios of male BPD patients in both two groups were higher, and the composition ratio of male BPD patients in high risk group was higher than that in low risk group (P<0.05).The composition ratio of married/cohabitant BPD patients in low risk group was higher than that in high risk group (P<0.05),while the composition ratio of single and unmarried patients in high risk group was higher than that in low risk group (P<0.05). The percentages of clinical symptoms such as hallucination, suspicion, moodiness, weird behavior, excitement and loquacity, wounding and destroying objects, going outside without a reason of the BPD patients in high risk group were higher than those in low risk group (P<0.05).The composition ratios of male patients [OR (95%CI)=1.925(1.093-3.390)],inpatients [OR (95%CI)=6.145(2.775-13.607)], lock-in [OR (95%CI) =3.178(1.523-6.629)], and drug noncompliance [OR (95%CI) =4.390(2.500-7.708)] of the BPD patients in high risk group were higher than those in low risk group (P<0.05).

Conclusion

Age, gender, source of patients, and medication compliance are the important influencing factors for the occurrence of risk behaviors of the BPD patients.Low age, female patients, community living patients, and regular medication play positive roles in the dowregulation of occurrence of risk behaviors of the BPD patients. The comprehensive and effective management models should be developed for the BPD patients to improve their quality of life.

Key words: Guangdong Province, bipolar disorder, risk behavior evaluation, influencing factors, Logistic regression

中图分类号: 

  • R749.3