吉林大学学报(医学版) ›› 2023, Vol. 49 ›› Issue (1): 203-208.doi: 10.13481/j.1671-587X.20230127

• 临床医学 • 上一篇    

肺良性转移性平滑肌瘤1例报告及文献复习

马梦诗1,2,陈鹏3,马忠森1()   

  1. 1.吉林大学第二医院呼吸内科,吉林 长春 130041
    2.吉林大学中日联谊医院核医学科,吉林 长春 130033
    3.吉林大学第二医院儿科,吉林 长春 130041
  • 收稿日期:2022-04-08 出版日期:2023-01-28 发布日期:2023-02-03
  • 通讯作者: 马忠森 E-mail:mazhongsen2005@163.com
  • 作者简介:马梦诗(1989-),女,辽宁省本溪市人,主治医师,医学硕士,主要从事肿瘤影像学方面的研究。
  • 基金资助:
    吉林省科技厅自然科学基金项目(20200201396JC);吉林省财政厅卫生专项项目(2020SCZT102)

Pulmonary benign metastasizing leiomyoma:A case report and literature review

Mengshi MA1,2,Peng CHEN3,Zhongsen MA1()   

  1. 1.Department of Respiratory and Critical Care Medicine,Second Hospital,Jilin University,Changchun 130041,China
    2.Department of Nuclear Medicine,China-Japan Union Hospital,Jilin University,Changchun 130033,China
    3.Department of Pediatrics,Second Hospital,Jilin University,Changchun 130041,China
  • Received:2022-04-08 Online:2023-01-28 Published:2023-02-03
  • Contact: Zhongsen MA E-mail:mazhongsen2005@163.com

摘要:

目的 探讨对无症状的绝经期肺良性转移性平滑肌瘤(PBML)患者不行任何治疗和仅定期随访的策略是否可行,为该病的诊断、治疗和预后提供参考。 方法 回顾性分析1例PBML患者的临床表现、检查结果和随访结果,并结合文献资料,探讨其发病机制和治疗措施。 结果 患者,女性,52岁。因体检发现双肺多发结节入院。既往因多发子宫平滑肌瘤行子宫全切术。入院后查体无明显肺部体征,影像学检查提示双肺多发类圆形结节状密度增高影。行左肺病灶电子计算机断层扫描(CT)引导下经皮穿刺肺内结节活检术,病理学检查诊断为PBML,且雌激素受体(ER)和孕激素受体(PR)阳性。患者性激素水平处于绝经期,遂未进行任何治疗,定期影像学检查随访。经皮肺穿刺术后5、11、20和34个月CT检查随访提示双肺结节未见明显增大,随访至41个月患者无不适症状。 结论 无症状且激素水平处于绝经期的女性PBML患者可不进行治疗,仅需进行定期影像学随访。

关键词: 良性转移性平滑肌瘤, 子宫肿瘤, 肿瘤转移, 肺肿瘤

Abstract:

Objective To explore the feasibility of the treatment strategy of no treatment and only regular follow-up for the patient with asymptomatic postmenopausal pulmonary benign metastasizing leiomyomat(PBML), and to provide a reference for the diagnosis, treatment, and prognosis of the disease. Methods The clinical characteristics, examination results, and follow-up results of a patient with PBML were analyzed retrospectively, and the pathogenesis and treatment measures were discussed in combination with the literature review. Results The female patient, 52 years old,was admitted to the hospital due to the physical examination of multiple nodules in both lungs, and previously underwent total hysterectomy for multiple uterine leiomyomas. There were no obvious pulmonary signs,and imaging examination showed multiple round nodular hyperdense shadows in both lungs. Percutaneous biopsy of pulmonary nodules was performed under the guidance of computed tomography (CT) in the left lung. The pathological diagnosis was PBML, and estrogen receptor(ER) and progesterone receptor(PR) were positive. The patient’s sex hormone level was in menopause,so no treatment was given, and regular imaging examinations and follow-up were carried out. The CT follow-up at 5, 11, 20, and 34 months after percutaneous lung puncture showed that no obvious enlargement of bilateral pulmonary nodules was found, and no cough, wheezing and other discomfort symptoms were found at 41 months. Conclusion The asymptomatic female PBML patients with hormone levels in menopause may not be treated and only need the regular imaging follow-up.

Key words: Benign metastasizing leiomyoma, Uterine neoplasms, Neoplasm metastasis, Lung neoplasms

中图分类号: 

  • R734.2