吉林大学学报(医学版) ›› 2022, Vol. 48 ›› Issue (1): 241-248.doi: 10.13481/j.1671-587X.20220131
收稿日期:
2020-12-10
出版日期:
2022-01-28
发布日期:
2022-01-17
通讯作者:
陈冰
E-mail:chenbing2020@jlu.edu.cn
作者简介:
刘昊川(1985-),男,吉林省长春市人,主治医师,在读博士研究生,主要从事临床骨科学和免疫学方面的研究。
基金资助:
Received:
2020-12-10
Online:
2022-01-28
Published:
2022-01-17
摘要:
红细胞人源化小鼠模型是一类能够稳定重建人红细胞的人源化小鼠,其对于人红细胞相关疾病临床前期研究起至关重要的作用。人源化小鼠模型的构建能够模仿人体免疫机能,在整体水平上反映人类生理和病理情况,探讨红细胞人源化小鼠模型的发展过程、构建方法及其在临床工作中的应用,可为后续优化该模型提供理论依据。现主要对人源化小鼠模型的发展、人源化小鼠人红细胞重建现状、人源化小鼠中人红细胞重建的影响因素、人红细胞相关疾病的研究和未来发展规划等几个方面进行综述。
中图分类号:
刘昊川,李新贺,陈冰. 红细胞人源化小鼠模型的构建及其临床应用研究进展Research progress in construction and its clinical application of humanized mouse model of red blood cells[J]. 吉林大学学报(医学版), 2022, 48(1): 241-248.
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