J4 ›› 2011, Vol. 37 ›› Issue (5): 923-926.

• 基础研究 • 上一篇    下一篇

不同分组间乳腺癌患者腋窝淋巴结转移的关联性分析

徐景伟|赵 慧|王振宇|明 鹏|王 琢   

  1. 吉林大学第二医院普通外科疾病诊疗中心|吉林 长春 130041
  • 收稿日期:2011-04-22 出版日期:2011-09-28 发布日期:2011-09-28
  • 通讯作者: 徐景伟(Tel:0431-88796572,E-mail:jingweixu2000@yahoo.com.cn) E-mail:jingweixu2000@yahoo.com.cn
  • 作者简介: 徐景伟(1967-)|男|吉林省扶余县人|医学硕士|副教授|副主任医师|主要从事乳腺癌早期诊断与综合治疗方面的研究。
  • 基金资助:

    吉林省长春市科技计划项目资助课题(08SF54)

Analysis on axillary lymph node metastasis of different groups of breast cancer patients

XU Jing-wei,ZHAO Hui|WANG Zhen-yu,MING Peng,WANG Zhuo   

  1. Center of General Surgery,Second Hospital| Jilin University,Changchun 1300
    41,China
  • Received:2011-04-22 Online:2011-09-28 Published:2011-09-28

摘要:

目的:分析不同分组间乳腺癌患者淋巴结转移的情况,探讨早期乳腺癌患者中进一步缩小腋窝清扫范围的可能性。方法:选择87例未接受任何新辅助治疗的可手术乳腺癌患者,按统一标准施行乳腺癌改良根治术,均在术中行完全腋窝淋巴结清扫。所获得的样本按淋巴结分组分为Ⅰ组、Ⅱ组、Ⅲ组和Rotter’s组,分别送检病理。分析各组淋巴结转移之间的关系。 结果:87例患者中,腋窝淋巴结阴性患者55例(63.2%),阳性患者32例(36.8%);Ⅰ组阴性患者中Rotter淋巴结转移1例,Ⅰ组淋巴结转移1~3枚24例;Ⅱ组阴性者22例(91.7%),Rotter淋巴结转移各1例(共8.3%);多于3枚7例,淋巴结阴性2例(28.6%),淋巴结转移1~3枚1例(14.3%),4~9枚3例(42.9%),多于9枚1例(14.3%);Ⅲ组淋巴结转移4例(57.1%)。结论:①对于无临床腋窝转移证据、术中探查未发现腋窝各组淋巴结转移的患者,理论上存在仅行Ⅰ组淋巴结清扫的可行性;②术中探查发现仅有腋窝LⅠ1~3个淋巴结转移的
患者,清扫范围至少达到LⅡ;③术中探查腋窝Ⅰ组淋巴结多于3枚阳性的患者,应结合Ⅱ组转移情况考虑
腋窝清扫范围,如Ⅱ组未发现转移,清扫范围应达到Ⅱ组;如Ⅱ组已经出现转移灶,应行全腋窝淋巴结清扫。

关键词: 乳腺肿瘤;腋窝淋巴结转移;腋窝淋巴结清扫术

Abstract:

Abstract:Objective To analyze the axillary lymph node metastasis of the different groups of breast cancer patients and  to explore  the opportunity to minimize the armpit circumscription in  early stage patients. Methods 80 breast cancer patients without any  neoadjuvant treatment were selected and treated with  standard modified radical mastectomy and received total axillary lymph node dissection. The lymph node samples were divided into four groups such  as level Ⅰ,level Ⅱ,level Ⅲ and Rotter’s lymph node  groups,then the  pathologic examination was performed. Results There were 55 (63.2%) patients with negative nodes and 32(36.8%) patients with positive nodes in total 87 patients. There was one patient with Rotter’s lymph node skip metastasis in level Ⅰ negative patients.There were 24 patients with 1-3 positive nodes in level Ⅰ group, and  there were 22(91.7%) patients with negative nodes in level Ⅱ group and there was one patient with positive Rotter’s lymph node in levels Ⅰ and Ⅱ groups(8.3% together). 7 patients had more than 3 positive nodes in level Ⅰ group, there were 2(28.6%) patients with negative nodes in level Ⅱ group,one patient (14.3%) with 1-3positive nodes,3 patients(42.9%) with 4-9 positive  nodes,one patient (14.3%) with more than 9 positive  nodes in level Ⅱ group and 4  patients with axillary lymph node metastasis in level Ⅲ group. Conclusion ①It  exists  the feasibility of giving level Ⅰ dissection to the patients with no clinical evidence of lymph node metastasis  and no findings of positive nodes in the procedure of operation. ②The patients with  1-3  positive  nodes in level Ⅰ group should accept a at least level Ⅱ dissection.③The patients with more than 3 positive nodes should accept levelⅡ cirumscription if there is no lymph node metastasis and should accept total armpit sirum soription if there is lymph node metastasis.

Key words: breast neoplasms; axillary lymph node metastasis; axillary lymphnode dissection

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