J4 ›› 2012, Vol. 38 ›› Issue (6): 1209-1213.

• 基础研究 • 上一篇    下一篇

DSA和MRA检测在亚急性自发性脑出血诊断中应用的价值比较

周明利1|冯骏2|屈天荣1   

  1. 1.西安交通大学医学院第一附属医院心血管科|陕西 西安 710061;
    2.西安交通大学医学院第一附属医院脑血管科|陕西 西安 710061
  • 收稿日期:2012-04-05 发布日期:2012-11-29
  • 通讯作者: 冯 骏(Tel:029-85323443,E-mail:1223134642@qq.com) E-mail:1223134642@qq.com
  • 作者简介:周明利(1963-)|女|陕西省西安市人|主管技师|医学本科|主要从事 心血管疾病的基础和临床研究。
  • 基金资助:

    陕西省科技厅科技攻关项目资助课题(2006K13-G7)

Comparison of |application value of DSA and MRA in diagnosis of  subacute spontaneous intracerebral hemorrhage

ZHOU Ming-li1|FENG Jun2|QU Tian-rong1   

  1. 1.Department of Cardiology,First Affiliated Hospital,Medical College,Xi’[KG-*3]an
     Jiaotong University,Xi’[KG-*3]an 710061,China;2.Department of Cerebral Vessels,First Affiliated Hospital| Medical College, Xi’an Jiaotong University,Xi’an 710061,China
  • Received:2012-04-05 Published:2012-11-29

摘要:

目的:探讨核磁共振血管造影(MRA)和数字减影血管造影(DSA)技术诊断亚急性期自发性脑出血患者脑血管结构异常的临床价值,为脑血管结构异常的检查提供临床依据。方法:选择亚急性自发性脑出血发病1周内的患者183例,使用DSA和MRA法检测亚急性自发性脑出血患者的基本结构血管异常。结果:MRA和DSA检测,顶叶、额叶和豆状核3个部位自发性脑出血的几率最大,分别占全部出血部位的17.5%、16.9%和14.2%;存在脑血管结构异常患者的年龄、高血压的发生率小于不存在脑血管结构异常患者(P<0.05),亚急性自发性脑出血与患者年龄、高血压发生率呈正相关关系(r=0.43,r=0.46,P<0.05);MRA和DSA检测脑血管畸形率差异无统计学意义;以DSA为诊断金标准,MRA检测脑血管畸形灵敏度特异度分别为98.8%和96.9%。 结论:  MRA与DSA均可应用于诊断亚急性自发性脑出血患者的血管结构异常,MRA有无创性的优势,更值得临床推广。

关键词: 亚急性自发性脑出血;核磁共振血管造影;数字减影血管造影

Abstract:

Objective To explore the clinical value of  digital subtractionangiography (DSA) and magnetic resonance angiography (MRA)  in diagnosis of cerebral vascular structural abnormalities in the  patients with spontaneous cerebral hemorrhage  in  subacute phase,and to provide clinical basis for detection of cerebral vascular structural abnormalities.Methods 183 patients with subacute spontaneous intracerebral hemorrhage within 1 week were selected,the vascular structures of the patients  were detected by DSA and MRA,and the influence factors were analyzed.Results The  DSA and MRA results showed that the  parietal lobe,frontal lobe,and lenticular nucleus had the largest incidence rates of spontaneous intracerebral hemorrhage,and accounted for 17.5%,16.9%,and 14.2%,respectively.he age and the incidence of the  hypertension of the  patients with cerebral vascular structural abnormalities were significantly lower than those of the patients without cerebral vascular structural abnormalities (P<0.05).There were positive correlations between subacute spontaneous cerebral hemorrhage and the age and the incidence of hypertension(r=0.43,r=0.46,P<0.05).The  rates of cerebrovascular alformation detected with  MRA and DSA had no  statistically significant difference.The DSA was regarded as detection gold standard,the sensitivites and specificities of   MRA  in detection of cerebrovascular malformation were 98.8% and 96.9%.Conclusion The abnormal vascular structures of patients with subacute spontaneous intracerebral hemorrhage  can be detected mostly by MRA and DSA.MRA has the advantages of non-invasion,which is worthy to be applied in clinic.

Key words: subacute spontaneous intracerebral hemorrhage;magnetic resonance angiography;digital subtraction angiography

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