1 |
RIORDAN J R, ROMMENS J M, KEREM B S, et al. Identification of the cystic fibrosis gene: cloning and characterization of complementary DNA [J]. Science, 1989, 245(4922): 1066-1073.
|
2 |
BESSONOVA L, VOLKOVA N, HIGGINS M, et al. Data from the US and UK cystic fibrosis registries support disease modification by CFTR modulation with ivacaftor[J]. Thorax, 2018, 73(8):731-740.
|
3 |
DRUMM M L, KONSTAN M W, SCHLUCHTER M D, et al. Genetic modifiers of lung disease in cystic fibrosis [J]. N Engl J Med, 2005, 353(14): 1443-1453.
|
4 |
CORVOL H, BLACKMAN S M, BOELLE P Y, et al. Genome-wide association meta-analysis identifies five modifier loci of lung disease severity in cystic fibrosis [J]. Nat Commun, 2015, 6: 8382.
|
5 |
EMOND M J, LOUIE T, EMERSON J, et al. Exome sequencing of extreme phenotypes identifies DCTN4 as a modifier of chronic Pseudomonas aeruginosa infection in cystic fibrosis[J]. Nat Genet, 2012, 44(8): 886-889.
|
6 |
XU Y, LIU C, CLARK J C, et al. Functional genomic responses to cystic fibrosis transmembrane conductance regulator (CFTR) and CFTR(delta508) in the lung[J]. J Biol Chem, 2006, 281(16):11279-11291.
|
7 |
DAVIS S, MELTZER P S. GEOquery: a bridge between the gene expression omnibus (GEO) and BioConductor [J]. Bioinformatics, 2007, 23(14): 1846-1847.
|
8 |
SMYTH G K. Limma: linear models for microarray data[M]//Bioinformatics and Computational Biology Solutions Using R and Bioconductor.New York:Spring Verlag,2005:397-420.
|
9 |
GU Z G, EILS R, SCHLESNER M. Complex heatmaps reveal patterns and correlations in multidimensional genomic data [J]. Bioinformatics, 2016, 32(18): 2847-2849.
|
10 |
YU G C, WANG L G, HAN Y Y,et al. ClusterProfiler: an R package for comparing biological themes among gene clusters[J]. OMICS, 2012, 16(5): 284-287.
|
11 |
SZKLARCZYK D, GABLE A L, LYON D, et al. STRING v11: protein-protein association networks with increased coverage, supporting functional discovery in genome-wide experimental datasets [J]. Nucleic Acids Res, 2019, 47(D1): D607-D613.
|
12 |
DEMCHAK B, HULL T, REICH M, et al. Cytoscape: the network visualization tool for GenomeSpace workflows[J].F1000Research,2014,3:151.
|
13 |
BANDETTINI W P, KELLMAN P, MANCINI C,et al.MultiContrast Delayed Enhancement (MCODE)improves detection of subendocardial myocardial infarction by late gadolinium enhancement cardiovascular magnetic resonance: a clinical validation study [J]. J Cardiovasc Magn Reson, 2012, 14(1): 83.
|
14 |
ISIDRO-SÁNCHEZ J, AKDEMIR D, MONTILLA-BASCÓN G. Genome-wide association analysis using R[J]. Methods Mol Biol, 2017, 1536: 189-207.
|
15 |
LEY K, HOFFMAN H M, KUBES P, et al. Neutrophils: New insights and open questions[J]. Sci Immunol, 2018, 3(30): eaat4579.
|
16 |
ADIB-CONQUY M, PEDRON T, PETIT-BERTRON A F, et al. Neutrophils in cystic fibrosis display a distinct gene expression pattern [J]. Mol Med, 2008, 14(1/2): 36-44.
|
17 |
DICKERHOF N, ISLES V, PATTEMORE P, et al. Exposure of Pseudomonas aeruginosa to bactericidal hypochlorous acid during neutrophil phagocytosis is compromised in cystic fibrosis [J]. J Biol Chem, 2019, 294(36): 13502-13514.
|
18 |
BRATCHER P E, ROWE S M, REEVES G, et al. Alterations in blood leukocytes of G551D-bearing cystic fibrosis patients undergoing treatment with ivacaftor [J]. J Cyst Fibros, 2016, 15(1): 67-73.
|
19 |
VAN KESSEL K P M, BESTEBROER J, VAN STRIJP J A G.Neutrophil-mediated phagocytosis of staphylococcus aureus [J]. Front Immunol, 2014, 5: 467.
|
20 |
KHAN M A, FARAHVASH A, DOUDA D N, et al. JNK activation turns on LPS- and gram-negative bacteria-induced NADPH oxidase-dependent suicidal NETosis [J]. Sci Rep, 2017, 7(1): 3409.
|
21 |
TAMASSIA N, BIANCHETTO-AGUILERA F, ARRUDA-SILVA F,et al.Cytokine production by human neutrophils: Revisiting the “dark side of the moon”[J]. Eur J Clin Invest, 2018, 48(): e12952.
|
22 |
CONTI H R, BRUNO V M, CHILDS E E, et al. IL-17 receptor signaling in oral epithelial cells is critical for protection against oropharyngeal candidiasis [J]. Cell Host Microbe, 2016, 20(5): 606-617.
|
23 |
MCGEACHY M J, CUA D J, GAFFEN S L.The IL-17 family of cytokines in health and disease [J]. Immunity, 2019, 50(4): 892-906.
|
24 |
SONG X Y, DAI D, HE X, et al. Growth factor FGF2 cooperates with interleukin-17 to repair intestinal epithelial damage[J]. Immunity, 2015,43(3): 488-501.
|
25 |
MACLEOD A S, HEMMERS S, GARIJO O, et al. Dendritic epidermal T cells regulate skin antimicrobial barrier function[J]. J Clin Invest, 2013, 123(10): 4364-4374.
|
26 |
CHEN X, CAI G, LIU C, et al. IL-17R-EGFR axis links wound healing to tumorigenesis in Lrig1+ stem cells [J]. J Exp Med, 2019, 216(1): 195-214.
|
27 |
O’NEILL L A J, ARTYOMOV M N. Itaconate: the poster child of metabolic reprogramming in macrophage function[J]. Nat Rev Immunol, 2019, 19(5): 273-281.
|
28 |
BENYELLES M, O’DONOHUE M F, KERMASSON L, et al. NHP2 deficiency impairs rRNA biogenesis and causes pulmonary fibrosis and Høyeraal-Hreidarsson syndrome [J]. Hum Mol Genet, 2020, 29(6): 907-922.
|
29 |
YU H, GUO W K, LIU Y D,et al. Immune characteristics analysis and transcriptional regulation prediction based on gene signatures of chronic obstructive pulmonary disease[J]. Int J Chron Obstruct Pulmon Dis, 2021, 16: 3027-3039.
|
30 |
YIN Y, WU Y Y, ZHANG X, et al. PPA1 regulates systemic insulin sensitivity by maintaining adipocyte mitochondria function as a novel PPARγ target gene [J]. Diabetes, 2021, 70(6): 1278-1291.
|
31 |
ONENGUT-GUMUSCU S, PAILA U, CHEN W M, et al. Novel genetic risk factors influence progression of islet autoimmunity to type 1 diabetes [J]. Sci Rep, 2020, 10: 19193.
|
32 |
AVERNA M, BAVESTRELLO M, CRESTA F,et al. Abnormal activation of calpain and protein kinase Cα promotes a constitutive release of matrix metalloproteinase 9 in peripheral blood mononuclear cells from cystic fibrosis patients [J]. Arch Biochem Biophys, 2016, 604: 103-112.
|
33 |
TURNBULL A R, PYLE C J, PATEL D F, et al. Abnormal pro-gly-pro pathway and airway neutrophilia in pediatric cystic fibrosis[J]. J Cyst Fibros, 2020, 19(1): 40-48.
|
34 |
HUAN C J, YANG T, LIANG J R, et al. Methylation-mediated BMPER expression in fibroblast activation in vitro and lung fibrosis in mice in vivo [J]. Sci Rep, 2015, 5: 14910.
|