间歇无氧运动对哮喘儿童呼吸功能和运动能力的改善作用

doi:10.13481/j.1671-587x.20160521

Abstract

Abstract:

Objective: To observe the effects of 8-week interval anaerobic training on the respiratory function, airway inflammatoion and exercise performance in the asthmatic children, and to provide theoretic and practical evidence for special exercise prescription for the asthmatic children. Methods: Forty-six mild asthmatic children were willingly divided into exercise group (n=23) and control group (n=23). The children in exercise group conducted 8 weeks interval anaerobic training while the children in control group maintained intrinsical lifestyle. Before and after experiment,the respiratory function, airway inflammatory reaction and exercise performance were determined by pneumonometer, nitric oxide determinator and cycle ergometer. Results: One patient of each group was lost to follow up.509 persons in exercise group finished the training; 11 persons had adverse reaction and the incidence was 2.2%. After experiment, compared with before experiment,the peak expiratory flow (PEF)in exercise group after experiment was increased (P<0.05), the fractional exhaled nitric oxide (FeNO) was decreased (P<0.05),the mean power (MP) and peak power (PP) in 30 s Wingate test were raised (P<0.05); there were no significant differences of all indicators in control group (P>0.05). Compared with control group after experiment, all indexes above (PEF, FeNO, MP and PP) in exercise group existed statistical differences (P<0.05). Conclusion: Interval anaerobic training has safetiveness and effectiveness under proper supervision and could improve the respiratory function, reduce the airway inflammation and enhance the exercise performance in the mild asthmatic children.

Key words: asthma, interval anaerobic training, respiratory function, airway inflammation, exercise performance

CLC Number:

R725.6

LI Guangxin, REN Lianzhu, YU Conghai, ZHAO Lijun. Improvement effect of interval training on respiratory function and exercise performance of asthmatic children[J].Journal of Jilin University Medicine Edition, 2016, 42(05): 949-953.

References

[1] Wood LG, Shivappa N, Berthon BS, et al. Dietary inflammatory index is related to asthma risk, lung function and systemic inflammation in asthma[J]. Clin Exp Allergy, 2015, 45(1):177-183.

[2] Sonnenschein-van der Voort AM, Howe LD, Granell R, et al. Influence of childhood growth on asthma and lung function in adolescence[J]. J Allergy Clin Immunol, 2015, 135(6):1435-1443.

[3] Jayasinghe H, Kopsaftis Z, Carson K. Asthma bronchiale and exercise-induced bronchoconstriction[J]. Respiration, 2015, 89(6):505-512.

[4] Westergren T, Ommundsen Y, Lødrup carlsen KC, et al. A nested case-control study:personal, social and environmental correlates of vigorous physical activity in adolescents with asthma[J]. J Asthma, 2015, 52(2):155-161.

[5] Wanrooij VH, Willeboordse M, Dompeling E, et al. Exercise training in children with asthma:a systematic review[J]. Br J Sports Med, 2014, 48(13):1024-1031.

[6] 黎涌明. 高强度间歇训练对不同训练人群的应用效果[J]. 体育科学, 2015,35(8):59-75.

[7] 中华医学会儿科学分会呼吸学组, 《中华儿科杂志》编辑委员会. 儿童支气管哮喘诊断与防治指南(2016年版)[J].中华儿科杂志, 2016, 54(3):167-181.

[8] St?nciulescu C, Chiru M, Oprea A, et al. The role of FeNO and spirometry in the evaluation of obstruction in pediatric asthma[J]. Pneumologia, 2015, 64(3):40-44.

[9] Tanaka H, Monahan KD, Seals DR. Age-predicted maximal heart rate revisited[J]. J Am Coll Cardiol, 2001, 37(1):153-156.

[10] Milanovic Z, SporišG, Weston M. Effectiveness of High-intensity interval training (HIT) and continuous endurance training for VO2 max improvements:a systematic review and meta-analysis of controlled trials[J]. Sports Med, 2015, 45(10):1469-1481.

[11] Forno E, Han YY, Muzumdar RH, et al. Insulin resistance, metabolic syndrome, and lung function in US adolescents with and without asthma[J]. J Allergy Clin Immunol, 2015, 136(2):304-311.

[12] Mendes FA, Almeida FM, Cukier A, et al. Effects of aerobic training on airway inflammation in asthmatic patients[J]. Med Sci Sports Exerc, 2011, 43(2):197-203.

[13] Eichenberger PA, Diener SN, Kofmehl R, et al. Effects of exercise training on airway hyperreactivity in asthma:a systematic review and meta-analysis[J]. Sports Med, 2013, 43(11):1157-1170.

[14] Moraes EZ, Trevisan ME, Baldisserotto Sde V, et al. Children and adolescents with mild intermittent or mild persistent asthma:aerobic capacity between attacks[J]. J Bras Pneumol, 2012, 38(4):438-444.

[15] Gomes EL, Carvalho CR, Peixoto-Souza FS, et al. Active video game exercise training improves the clinical control of asthma in children:randomized controlled trial[J]. PLoS One, 2015, 10(8):e0135433.

Improvement effect of interval training on respiratory function and exercise performance of asthmatic children

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