磁共振弥散加权成像ADC和rADC在腮腺良恶性肿瘤鉴别诊断中的应用

doi:10.13481/j.1671-587x.20200632

Abstract

Abstract: Objective

To investigate the diagnostic value of apparent diffusion coefficient （ADC） and apparent diffusion coefficient ratio （rADC）of diffusion weighted imaging（DWI） in the differentiation of benign and malignant parotid tumors.

Methods

Eighty-four patients with parotid gland tumor confirmed by pathology were selected. According to the postoperative pathological types， the patients were divided into benign tumor group and malignant tumor group.The patients received preoperative routine MRI and DWI sequence scanning.HE staining was used to detect the pathomorphology of benign and malignant parotid gland tumors and their parotid gland tumor tissue with different pathological types，and the ADC of benign and malignat parotid gland tumors and their adjacent glands of and contralateral glands of were measured， respectively.The corresponding rADC were calculated.

Results

There were 60 cases of benign parotid gland tumor and 24 cases of malignant parotid gland tumor；the benign tumor had the clear multi-boundary， and the mixed tumor and the adenomas were the most common types；the T2WI results showed the isostatic and low-signal lesions； the malignant parotid gland tumor was more common in mucoepidermoid carcinoma with irregular morphology， blurred boundaries and uneven signals， usually accompanied by invasion of peripheral structures and enlargement of cervical lymph nodes. Compared with benign parotid gland tumor，the ADC of parotid gland malignant tumor was decreased（P<0.05），and the rADC of contralateral glands and adjacent glands of parotid malignant tumor were decreased （P<0.05）；the ROC curve detection results showed that the area under the curves （AUC） of ADC， rADC of contralateral，glands， and rADC of adjacent glands were 0.859， 0.874，and 0.894， respectively.The AUC of ADC and contralateral glands and the AUC of ADC and adjacent glands were 0.874 and 0.894 calculated by combined multiple indexes.

Conclusions

The ADC and rADC of DWI can provide the reference for the diagnosis and differential diagnosis of benign and malignant parotid gland tumors， which has important clinical significance.

Key words: parotid gland tumor, magnetic resonance imaging, diffusion weighted imaging, apparent diffusion coefficient, apparent diffusion coefficient ratio

CLC Number:

R739.87

Lingxue SHI,Shuo LIU,Xuewei ZHENG,Xiaoliang CHENG,Zhaohui CHEN,Baolin MA,Hongguo ZHANG,Jun DING. Application of magnetic resonance diffusion weighted imaging ADC and rADC in differential diagnosis of benign and malignant parotid gland tumors[J].Journal of Jilin University(Medicine Edition), 2020, 46(6): 1309-1314.

Figures/Tables 7

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References 22

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Group	n	ADC （×10^－3mm²·s^－1）	rADC of contralateral gland	rADC of adjacent gland
Benign parotid gland tumor	60	1.21±0.25	0.11±0.27	0.20±0.30
Malignant parotid gland tumor	24	0.90±0.12	－0.24±0.14	－0.19±0.14
t		7.053	7.097	7.239
P		<0.01	<0.01	<0.01

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Application of magnetic resonance diffusion weighted imaging ADC and rADC in differential diagnosis of benign and malignant parotid gland tumors

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