Journal of Jilin University(Medicine Edition) ›› 2021, Vol. 47 ›› Issue (3): 630-636.doi: 10.13481/j.1671-587X.20210312
• Research in basic medicine • Previous Articles Next Articles
Bo MA(),Jiangang LI,Jun WANG,Junli HOU,Liang LI
Received:
2020-10-10
Online:
2021-05-28
Published:
2021-05-28
Contact:
Bo MA
E-mail:1401596054@qq.com
CLC Number:
Bo MA, Jiangang LI, Jun WANG, Junli HOU, Liang LI. Promotion effect of miR-106b on invasion and migration of colon cancer cells through targeting TGF-β/Smad pathway[J].Journal of Jilin University(Medicine Edition), 2021, 47(3): 630-636.
Tab.2
Number of invasion cells and expression levels of p-Smad2 and p-Smad3 proteins in SW-480 cells in various groups"
Group | Number of invasion cells | p-Smad2 protein | p-Smad3 protein |
---|---|---|---|
Blank vector | 169.2±12.3 | 1.22±0.01 | 1.34±0.02 |
miR-106b | 265.4±20.3* | 0.30±0.01* | 0.23±0.01* |
pGL3-TGF-βR1 | 124.8±17.6*△ | 2.63±0.02* | 2.54±0.12* |
miR-106b-mimics+pGL3-TGF-βR1 | 177.6±13.4△# | 1.51±0.06△# | 1.38±0.09△# |
F | 24.521 | 174.532 | 207.348 |
P | <0.01 | <0.01 | <0.01 |
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