Abstract:

Oligodendroglioma （ODG） is a primary glioma that frequently occurs in the frontal lobe of the brain and is associated with a relatively favorable patient prognosis. With technological advancements， the diagnosis of ODG is no longer limited to computed tomography（CT） and magnetic resonance imaging（MRI）， as artificial intelligence and imaging technologies have improved diagnostic accuracy. Pathological and molecular marker diagnostics provide a more precise basis for grading ODG and developing personalized treatment strategies. Currently， significant differences exist in the choice of ODG treatment approaches across different countries or regions. In China， surgical resection remains the core treatment for ODG. Depending on the ODG patients’ specific condition and individual differences after operation， the clinicians can select radiotherapy and/or chemotherapy as adjunctive treatments. Novel therapies such as immunotherapy， tumor-treating fields（TTFields）， and targeted therapy have been applied in clinical practice or are under investigation. Additionally， emerging strategies such as bioactive substance nanocarrier technology and drug repurposing offer new possibilities for treatment. Through the literature review， this article systematically summarized domestic and international diagnostic methods and treatment modalities for ODG， aiming to enhance the precision of its diagnosis and treatment.

Key words: Oligodendroglioma, Diagnosis, Targeted therapy, Immunotherapy, Radiotherapy, Chemotherapy