J4 ›› 2012, Vol. 38 ›› Issue (6): 1191-1195.

• 临床医学 • 上一篇    下一篇

经皮血管腔内血管成形术治疗下肢动脉硬化闭塞症患者的疗效及安全性评价

何 凡|蔡进中|王露平|窦永充|陈旭东   

  1. (暨南大学第二临床医学院 深圳市人民医院介入科|广东 深圳 518002)
  • 收稿日期:2012-06-20 发布日期:2012-11-28
  • 通讯作者: 陈旭东(Tel:0755-25533018-8100,E-mail:chenxudong999@126.com) E-mail:chenxudong999@126.com
  • 作者简介:何 凡(1983-)|男|重庆市人|住院医师|医学硕士|主要从事介入诊断与治疗方面的研究。
  • 基金资助:

    广东省中医药局中医药强省科研立项基金资助课题(2007246)

Analysis on curative effects of percutaneous transluminalangioplasty in |treatment of patients with arteriosclerosis obliteration of lower extremity

HE Fan,CAI Jin-zhong,WANG Lu-ping,DOU Yong-chong,CHEN Xu-dong   

  1. Department of Interventional Radiology,Second Medical College,Jinan University,People’Hospital of Shenzhen,Shenzhen 518002,China
  • Received:2012-06-20 Published:2012-11-28

摘要:

目的:评价经皮血管腔内血管成形术(PTA)治疗下肢动脉硬化闭塞症患者的临床疗效及安全性,为提高下肢动脉硬化闭塞症的手术成功率提供临床依据。 方法:下肢动脉硬化闭塞症患者30例,其中Fontain分期Ⅱ期患者11例,Ⅲ期患者7例,Ⅳ期患者12例,观察所有患者术中血管再通及治疗前后临床症状改善情况。 结果:30例患者45支血管行PTA,成功开通42支血管,手术成功率为93.3%。开通血管中行超声斑块消融术血管10支,超声斑块消融+球囊成形术血管20支,超声斑块消融+球囊成形术+支架植入术血管12支。27例患者治疗后临床症状改善,其中FontainⅡ期患者11例(11/11),Ⅲ期患者7例(7/7),Ⅳ期患者9例(9/12)。FontainⅡ、Ⅲ期患者术后临床有效率比较差异无统计学意义(P>0.05),Ⅱ、Ⅲ期患者术后临床有效率高于Ⅳ期患者(P<0.05)。30例患者中仅1例发生严重并发症,无死亡患者。结论:多种血管腔内血管成形术联合应用可以提高下肢动脉硬化闭塞症的手术成功率;PTA治疗下肢动脉硬化闭塞症安全有效。

关键词: 下肢动脉硬化闭塞症;经皮血管腔内血管成形术;超声斑块消融术;球囊成形术

Abstract:

Abstract:Objective To evaluate the efficacy and  safety of percutaneous transluminal  angioplasty (PTA) in  treatment of patients with arteriosclerosis obliteration of lower extremity,and to provide clinical evidence to improve the operation  success rate of  arteriosclerosis obliteration of lower extremity.Methods 30 patients with rteriosclerosis obliteration of lower extremity(FontainⅡ-Ⅳ stage) were submitted to PTA,in which 11 patients were FontainⅡ,7 patients were Fontain Ⅲ,12  patients wereFontain Ⅳ. The recanalization of occlusion arteries and the improvement of clinical symptoms before and after  operation were observed. Results 45 lower extrem
ity arteries in 30 patients were performed with  PTA.42 lower extremity arteries were successfully recanalized,the opoeration  success rate was 93.3%.In 42 recanalized lower extremity arteries,10 were performed with  intravascular ultrasound ablation,20 were  performed with  intravascular ultrasound ablation +balloon  angiography,12 were performed with  intravascular ultrasound ablation +ballon angiography+stenting.The  clinical symptoms  were ameliorated in 27 patients,in which 11 were Fontain Ⅱ(11/11),7 were Fontain Ⅲ(7/7),9 were Fontain Ⅳ(9/12),so the clinical effective  rate was 90%.There was no significant difference of short-term clinical effective rate  between Fontain Ⅱ and Fontain Ⅲ patients (P>0.05).The short-term clinical effective rates were  significantly different between Fontain Ⅱ,Ⅲ and  Fontain Ⅳ patients (P<0.05). Conclusion Combined treatment of   a variety of endovascular angioplasty  could improve the operation success rate of arteriosclerosis obliteration of lower extremity.PTA is a feasible and effective technique for curring arteriosclerosis obliteration of lower xtremity.

Key words: arteriosclerosis obliteration of lower extremity, percutaneous transluminal angioplasty;intravascular ultrasound ablation;balloon , angioplasty

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