[1] HORI S, NOMURA T, SAKAGUCHI S. Control of regulatory T cell development by the transcription factor Foxp3[J]. Science, 2003, 299(5609):1057-1061. [2] FONTENOT J D, GAVIN M A, RUDENSKY A Y. Foxp3 programs the development and function of CD4+CD25+ regulatory T cells[J]. Nat Immunol, 2003, 4(4):330-336. [3] KHATTRI R, COX T, YASAYKO S A, et al. An essential role for Scurfin in CD4+CD25+ T regulatory cells[J]. Nat Immunol, 2003, 4(4):337-342. [4] TANAKA A, SAKAGUCHI S. Regulatory T cells in cancer immunotherapy[J]. Cell Res, 2017, 27(1):109-118. [5] ELEONORA T, ILENIA P, VALERIA S, et al. Regulatory T cells with multiple suppressive and potentially pro-tumor activities accumulate in human colorectal cancer Oncoimmunology[J]. Oncoimmunology, 2016, 5(7):e1175800. [6] GILLIET M, LIU Y J. Human plasmacytoid-derived dendritic cells and the induction of T-regulatory cells[J]. Hum Immunol, 2002, 63(12):1149-1155. [7] MOSEMAN E A, LIANG X Q, DAWSON A J, et al. Human plasmacytoid dendritic cells activated by CpG oligodeoxynucleotides induce the generation of CD4+CD25+ regulatory T cells[J]. J Immunol, 2004, 173(7):4433-4442. [8] SUN C M, HALL J A, BLANK R B, et al. Small intestine lamina propria dendritic cells promote de novo generation of Foxp3 Treg cells via retinoic acid[J]. J Exp Med, 2007, 204(8):1775-1785. [9] PALUCKA K, UENO H, FAY J, et al. Dendritic cells and immunity against cancer[J]. J Intern Med,2011,269(1):64-73. [10] TARBELL K V, PETIT L, ZUO X, et al. Dendritic cell-expanded, islet-specific CD4+CD25+CD62L+regulatory T cells restore normoglycemia in diabetic NOD mice[J].J Exp Med, 2007, 204(1):191-201. [11] LIU Y J. A unified theory of central tolerance in the thymus[J]. Trends Immunol, 2006, 27(5):215-221. [12] SHI C, ZHANG Y, YANG H, et al. Ultrasound-targeted microbubble destruction-mediated Foxp3 knockdown may suppress the tumor growth of HCC mice by relieving immunosuppressive Tregs function[J]. Exp Ther Med, 2018, 15(1):31-38. [13] WOO E Y, CHU C S, GOLETZ T J, et al. Regulatory CD4+CD25+ T cells in tumors from patients with early-stage non-small cell lung cancer and late-stage ovarian cancer[J]. Cancer Res,2001,61(12):4766-4772. [14] LIYANAGE U K, MOORE T T, JOO H G, et al. Prevalence of regulatory T cells is increased in peripheral blood and tumor microenvironment of patients with pancreas or breast adenocarcinoma[J]. J Immunol, 2002, 169(5):2756-2761. [15] YAMAZAKI S, PATEL M, HARPER A, et al. Effective expansion of alloantigen-specific Foxp3+ CD25+ CD4+ regulatory T cells by dendritic cells during the mixed leukocyte reaction[J]. Proc Natl Acad Sci U S A, 2006, 103(8):2758-2763. [16] YU A X, SNOWHITE I, VENDRAME F, et al. Selective IL-2 responsiveness of regulatory T cells through multiple intrinsic mechanisms supports the use of low-dose IL-2 therapy in type 1 diabetes[J]. Diabetes, 2015, 64(6):2172-2183. [17] SHI C Y, ZHANG Y, YANG H C, et al. Ultrasound-targeted microbubble destruction-mediated Foxp3 knockdown may suppress the tumor growth of HCC mice by relieving immunosuppressive Tregs function[J].Exp Ther Med, 2018, 15(1):31-38. [18] SATO E, OLSON S H, AHN J, et al. Intraepithelial CD8+ tumor-infiltrating lymphocytes and a high CD8+/regulatory T cell ratio are associated with favorable prognosis in ovarian cancer[J]. Proc Natl Acad Sci U S A, 2005, 102(51):18538-18543. [19] TROJANDT S, BELLINGHAUSEN I, RESKE-KUNZ A B, et al. Tumor-derived immuno-modulators induce overlapping pro-tolerogenic gene expression signatures in human dendritic cells[J].Hum Immunol, 2016, 77(12):1223-1231. [20] LEGITIMOA,CONSOLINI R,FAILL A,et al.Dendritic cell defects in the colorectal cancer[J].Human vaccines Immunotherapeut,2014,10(11):3224-3235. [21] LOHELA M, CASBON A J, OLOW A, et al. Intravital imaging reveals distinct responses of depleting dynamic tumor-associated macrophage and dendritic cell subpopulations[J].Proc Natl Acad Sci U S A, 2014, 111(47):E5086-E5095. [22] THOMAS S N, VOKALI E, LUND A W, et al. Targeting the tumor-draining lymph node with adjuvanted nanoparticles reshapes the anti-tumor immune response[J].Biomaterials, 2014, 35(2):814-824. [23] BRACAMONTE-BARAN W, FLORENTIN J, ZHOU Y, et al. Modification of host dendritic cells by microchimerism-derived extracellular vesicles generates split tolerance[J]. Proc Natl Acad Sci U S A, 2017, 114(5):1099-1104. |