[1] Chow JM,Huang GC,Shen SC,et al.Differential apoptotic effect of Wogonin and nor-Wogonin via stimulation of ROS production in human leukemia cells[J]. J Cell Biochem,2008,103 (5):1394-1404.[2] Lin YT,Yang JS,Lin HJ,et al. Baicalein induces apoptosis in SCC-4 human tongue cancer cells via a Ca2+-dependent mitochondrial path way [J].In Vivo,2007,21(6): 1053-1058.[3] 毛 捷,徐善水,盛莉莉,等.黄芩素的抗肿瘤作用及机制的研究进展[J].中国临床药理学与治疗学,2009,14(10) :1178-1182.[4] Ma GZ,Liu CH,Wei B,et al.Baicalein inhibits DMBA/TPA-induced skin tumorigenesis in mice by modulating proliferation,apoptosis,and inflammation[J].Inflammation,2013,36(2): 457-467.[5] Miocinovicr R,Mccabe N,Keck R,et al. In vivo and in vitro effect of baicalein on human prostate cancer cells[J]. Int J Oncol,2005,26 (1): 241-246.[6] Taniguchi H,Yoshida T,Horinaka M,et al. Baicalein over comes tumor necrosis factor-related apoptosis-inducing ligand resistance via two different cell-specific pathways in cancer cellsbut not innormal cells[J]. Cancer Res,2008,68 (21):8918-8927.[7] 姚 蕾,钟淑霞,兰珊珊,等.黄芩苷联合NB-UVB对黑素细胞黑素合成及酪氨酸酶活性的影响[J].吉林大学学报:医学版,2014,40(5):1024-1027.[8] Bernard WS,Christopher PW.World cancer report 2014[M].Lyon:International Agency for Research on Cancer,2014.[9] Siegel R,DeSantis C,Jemal A.Colorectal cancer statistics,2014[J].CA Cancer J Clin,2014,64(2): 104-117.[10] Chen WC,Kuo TH,Tzeng YS,et al.Baicalin induces apoptosis in SW620 human colorectal carcinoma cells in vitro and suppresses tumor growth in vivo[J].Molecules,2012,17(4): 3844-3857.[11] 陈红锦.黄芩苷干预错配修复基因功能缺失的裸鼠结肠原位移植瘤的作用及分子机制研究[D].南京:南京中医药大学,2013.[12] Fu Z,Di Y,Gao L,et al.The Drug Metabolism and Pharmacokinetics Investigation about Baicalin Effect and Baicalein on Mice U14 Cervical Cancer [J].J Spectrosc,2015.doi:10.1155/2015/632062.[13] Feng J,Guo C,Zhu Y,et al.Baicalin down regulates the expression of TLR4 and NFkB-p65 in colon tissue in mice with colitis induced by dextran sulfate sodium [J].Int J Clin Exp Med,2014,7(11): 4063-4072.[14] Wang W,Guo QL,You QD,et al.The anticancer activities of Wogonin in murine sarcoma S180 both in vitro and in vivo[J].Biol Pharm Bull,2006,29(6):1132-1137.[15] 杨 明,钟锐生,陈桂红.黄芩苷对人鼻咽癌CNE-2Z细胞生长的抑制作用[J].广东药学院学报,2011,27(4):400-403.[16] Eskes R,Desagher S,Antonsson B,et al.Bid induces the oligomerization and insertion of Bax into the outermitochondrial membrane [J].Mol Cell Biol,2000,20 (3): 929-935.[17] Miramar MD,Costantini P,Ravagnan L,et al.NADH oxidase activity of mitochondrial apoptosis-inducing factor [J].J Biol Chem,2001,276 (19): 16391-16398.[18] Chandrashekar N,Selvamani A,SubramanianR,et al.Baicaleinin hibits pulmonary carcinogenesis-associated inflammation and interferes with COX-2,MMP-2 and MMP-9 expressions in-vivo[J]. Toxicol Appl Pahrmacol,2012,261 (1):10-21.[19] Jarskog LF,Selinger ES,Lieberman JA,et al.Apoptotic proteins in the temporal cortex in schizophrenia: high Bax/Bcl-2 ratio without caspase-3 activation[J].Am J Psychiatry,2004,161(1):109-115.[20] Floyd DH,Zhang Y,Dey BK,et al.Novel anti-apoptotic microRNAs 582-5p and 363 promote human glioblastoma stem cell survival via direct inhibition of caspase 3,caspase 9,and Bim[J].PLoS One,2014,9(5): e96239.[21] 沈艺南,黄晟宇,胡贤荣,等.腹腔镜肝切除术治疗结肠癌肝转移的系统评价[J].临床肝胆病杂志,2014,30(12):1287-1291. |