以头痛为首发症状的嗜铬细胞瘤1例报告并文献复习

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Pheochromocytoma with headache as first symptom: A case report and literature review

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doi:10.13481/j.1671-587x.20150530

Abstract:

Objective To study the clinical manifestation and the diagnosis methods of one case of pheochromocytoma with headache as the first clinical feature. Methods The clinical symptoms were recorded;radio immunoassay was used to detect the active renin of the patient;chemiluminescence was used to detect the aldosterone level of the patient;high performance liquid chromatography was used to detect the levels of blood adrenaline and noradrenaline;CT was used to detect the adrenal gland;the tumor tissue was taken by operation and pathological examination and HE staining were performed. Results When the patient suffered serious headache,the levels of active renin,aldosterone and blood pressure were increased obviously.The CT results showed that the patient's left adrenal gland had a quasi-circular low density.On the CT enhanced scan image, the tumor appeared inhomogeneous enhancement on artery phase.There were transparent and eosinophil cells arranged in a prominent nesting pattern and bundles with obvious bleeding and necrosis and also there were some heterocysts. Conclusion Pheochromocytoma is a catecholamine-producing endocrine tumor and a reliable diagnosis can be made by combining the clinical information,biochemical testing,imaging examination and pathology.

Key words: pheochromocytoma, headache, hypertension

CLC Number:

R739.41

XU Lisi, HE Jinting, MANG Jing, WANG Xueju, WANG Liping, NA Wanli, SHAO Yankun, XU Zhongxin. Pheochromocytoma with headache as first symptom: A case report and literature review[J].Journal of Jilin University Medicine Edition, 2015, 41(05): 1027-1031.

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[13] 王佳, 高峰,张春兵.川芳嗪降低咖啡因诱导的PC12细胞凋亡的研究[J].长春中医药大学学报,2014,30(2):14-17.

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