| [1] Ravi M,Paramesh V,Kaviya SR,et al. 3D cell culture systems:advantages and applications[J]. J Cell Physiol,2015,230(1):16-26.[2] Lovitt CJ,Shelper TB,Avery VM.Evaluation of chemotherapeutics in a three-dimensional breast cancer model[J].J Cancer Res Clin Oncol,2015,141(5):951-959.[3] Dawson MA,Kouzarides T.Cancer epigenetics:from mechanism to therapy[J].Cell,2012,150(1):12-27.[4] Teoh-Fitzgerald ML, Fitzgerald MP,Zhong W,et al.Epigenetic reprogramming governs EcSOD expression during human mammary epithelial cell differentiation,tumorigenesis and metastasis[J]. Oncogene,2014,33(3):358-368.[5] DesRochers TM,Shamis Y,Alt-Holland A,et al. The 3D tissue microenvironment modulates DNA methylation and E-cadherin expression in squamous cell carcinoma[J]. Epigenetics,2012,7(1):34-46.[6] Cheung KJ,Ewald AJ.Illuminating breast cancer invasion:diverse roles for cell-cell interactions[J]. Curr Opin Cell Biol,2014,30C:99-111.[7] You JS,Jones PA.Cancer genetics and epigenetics:two sides of the same coin[J].Cancer Cell,2012,22(1):9-20.[8] Goel A,Boland CR.Epigenetics of colorectal cancer[J].Gastroenterology,2012,143(6):1442-1460.[9] Bissell MJ,Kenny PA,Radisky DC.Microenvironmental regulators of tissue structure and function also regulate tumor induction and progression:the role of extracellular matrix and its degrading enzymes[J].Cold Spring Harb Symp Quant Biol,2005,70:343-356.[10] Benton G,Crooke E,George J.Laminin-1 induces E-cadherin expression in 3-dimensional cultured breast cancer cells by inhibiting DNA methyltransferase 1 and reversing promoter methylation status[J]. FASEB J,2009,23(11):3884-3895.[11] Baranwal S,Alahari SK.Rho GTPase effector functions in tumor cell invasion and metastasis[J]. Curr Drug Targets,2011,12(8):1194-1201.[12] Luis-Ravelo D,Anton I,Zandueta C,et al. RHOB influences lung adenocarcinoma metastasis and resistance in a host-sensitive manner[J]. Mol Oncol,2014,8(2):196-206.[13] Ellenbroek SI,Collard JG.Rho GTPases:functions and association with cancer[J].Clin Exp Metastasis,2007,24(8):657-672. |
