关键词: 纳米载银无机抗菌剂；室温固化；聚甲基丙烯酸甲酯；抗菌率；球磨法

Abstract:

Abstract:Objective To investigate the antibacterial effect of room curing polymethylmethacrylate(PMMA) material adding nano-silver base inorganic antibacterial agent and to detect the changes of its mechanical property.
Methods Nano-silver base inorganic antibacterial agent was added to the room curing PMMA material in the range of 0.5%-3.0% at an interval of 0.5% by ball milling to make specime.Antibacterial rates of the specimes were detected by film method.Bending strength,impact strength,and wear resistance of the specimes were respectively detected on electronic universal testing machine,impact test machine and friction and wear test machine.Results The antibacterial rates of Streptococcus mutans and Candida albicans were more than 50% when antibiotics content was 1.0%.The antibacterialrates of Streptococcus mutans and Candida albicans were more than 90% when the antibiotics content was 2.5%.The three mechanical properties were increased compared with control group when the antibacterial agents were in the range of 1.0%-1.5%.Then the three mechanical properties were decreased with the increasing of antimicrobial concentration.When the antibiotics content was 2.0%,the wear resistance had significant difference compared with  control group  (P<0.05); when the antibiotics content was 2.5%,the bending strength and impact strength had significant difference  compared with  control group(P<0.05).Conclusion The antibacterial effect of room curing PMMA adding nano-silver base inorganic antibacterial agent is ideal.The antibacterial rate is increased gradually with the increasing content of antibacterial agents.There is no significant effect on the mechanical properties of room curing PMMA material,but the antibacterial  effects are satisfied when the content of antibacterial agents is 2.0%.

Key words: nano-silver base inorganic antibacterial agent, room temperature curing, polymethylmethacrylate, antibacterial rate, ball milling method